Styrene

Styrene

SCHEMBL9614715

C=Cc1ccccc1.CCCCCS(=O)(=O)O

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
TSHR P16473 1/20 0.45
LMNA P02545 2/20 0.43
EGFR P00533 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
EPHX2 P34913 1/20 0.40
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
S1PR2 O95136 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
MMP1 P03956 1/20 0.37
MMP9 P14780 1/20 0.37
MMP13 P45452 1/20 0.37
NAAA Q02083 3/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1548479 0.97 EGFR (0.43) ALDH1A1TSHRLMNAEGFRTDP1
Styrene SCHEMBL27660332 0.88 ALDH1A1 (0.50) ALDH1A1TSHRLMNAEGFRTDP1
Styrene SCHEMBL5872365 0.87 ALDH1A1 (0.48) ALDH1A1TSHRLMNAEGFRTDP1
Styrene SCHEMBL27297424 0.84 EGFR (0.43) ALDH1A1TSHRLMNAEGFRTDP1
Styrene SCHEMBL4587092 0.84 ALDH1A1 (0.58) ALDH1A1TSHRLMNATDP1MEN1
Styrene SCHEMBL10931561 0.84 ALDH1A1 (0.58) ALDH1A1TSHRLMNATDP1MAPT
Styrene SCHEMBL10715462 0.82 ALDH1A1 (0.67) ALDH1A1TSHRLMNAEGFRTDP1
Styrene SCHEMBL1194200 0.82 ALDH1A1 (0.67) ALDH1A1TSHRLMNAEGFRTDP1
Styrene SCHEMBL11801013 0.82 ALDH1A1 (0.67) ALDH1A1TSHRLMNAEGFRTDP1
Styrene SCHEMBL5872084 0.81 ALDH1A1 (0.50) ALDH1A1TSHRLMNAEGFRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0483344-A4 METHOD OF REMOVING AND CRYSTALLIZING CATION RESIN ADSORBED CALCIUM AND MAGNESIUM 1992-11-04 EP disclosed
EP-0483344-A1 METHOD OF REMOVING AND CRYSTALLIZING CATION RESIN ADSORBED CALCIUM AND MAGNESIUM AMERICAN PEMBROKE, INC. (US) 1992-05-06 EP disclosed
WO-1991017831-A1 METHOD OF REMOVING AND CRYSTALLIZING CATION RESIN ADSORBED CALCIUM AND MAGNESIUM AMERICAN PEMBROKE, INC. (US) 1991-11-28 WO disclosed
US-5021216-A Method of removing and crystallizing cation resin absorbed calcium and magnesium AMERICAN PEMBROKE, INC. (US) 1991-06-04 US disclosed
EP-0068413-B1 METHOD OF USING HIGHER CONCENTRATION SULFURIC ACID FOR STRIPPING AND PRECIPITATION OF ADSORBED MAGNESIUM AMERICAN PETRO MART, INC. (US) 1985-09-11 EP disclosed
US-4493907-A Method of using higher concentration sulfuric acid for stripping and precipitation of adsorbed magnesium AMERICAN PETRO MART, INC. (US) 1985-01-15 US disclosed
EP-0068413-A2 Method of using higher concentration sulfuric acid for stripping and precipitation of adsorbed magnesium AMERICAN PETRO MART, INC. (US) 1983-01-05 EP disclosed