Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31476387 | 0.85 | IDO1 (0.47) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL5911692 | 0.85 | CYP3A4 (0.47) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL5773097 | 0.85 | CYP3A4 (0.47) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL241692 | 0.85 | IDO1 (0.47) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL27689825 | 0.83 | IDO1 (0.46) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL15456282 | 0.83 | IDO1 (0.46) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL6204787 | 0.81 | IDO1 (0.44) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL1285074 | 0.81 | MEN1 (0.47) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL20612473 | 0.81 | IDO1 (0.48) | IDO1TDO2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL20764854 | 0.81 | IDO1 (0.44) | IDO1TDO2ALDH1A1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102140088-A | New process for synthesizing 3-bromobenzaldehyde acetal | WUHAN ZHENGQINHE ENVIRONMENTAL PROT TECHNOLOGY CO LTD | 2011-08-03 | — | — | CN | claimed |
| EP-0289669-B1 | PROCESS FOR PREPARING 3-PHENOXYBENZALDEHYDES | HARDWICKE CHEMICAL COMPANY (US) | 1992-04-01 | — | — | EP | claimed |
| EP-0289669-A1 | Process for preparing 3-phenoxybenzaldehydes | HARDWICKE CHEMICAL COMPANY (US) | 1988-11-09 | — | — | EP | claimed |
| US-4691033-A | Process for preparing 3-phenoxybenzaldehydes | HARDWICKE CHEMICAL COMPANY (US) | 1987-09-01 | — | — | US | claimed |
| CN-105792832-B | Organic compounds for the treatment of hepatitis B virus | 诺华股份有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-109251189-B | 3-piperazinyl chalcone derivatives, pharmaceutical compositions thereof and application thereof | 华东理工大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-107090000-B | A kind of derivative of 7 fatty acid of benzo borazol and its preparation and purposes | 上海交通大学 | 2019-07-12 | — | — | CN | disclosed |
| CN-109251189-A | 3 piperazinyl chalcone derivatives, its pharmaceutical composition and its application | 华东理工大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-107090000-A | A kind of derivative and its preparation and medicinal usage of 7 aliphatic acid of benzo borazol | 上海交通大学 | 2017-08-25 | — | — | CN | disclosed |
| US-9345708-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-05-24 | — | — | US | disclosed |
| US-8829007-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-09-09 | — | — | US | disclosed |
| CN-102140088-A | New process for synthesizing 3-bromobenzaldehyde acetal | WUHAN ZHENGQINHE ENVIRONMENTAL PROT TECHNOLOGY CO LTD | 2011-08-03 | — | — | CN | disclosed |
| EP-0976732-A1 | 1,4-SUBSTITUTED CYCLIC AMINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1999032100-A2 | PHARMACEUTICAL COMPOSITION FOR ANTAGONIZING CCR5 COMPRISING ANILIDE DERIVATIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |
| WO-1999032468-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |
| EP-0289669-B1 | PROCESS FOR PREPARING 3-PHENOXYBENZALDEHYDES | HARDWICKE CHEMICAL COMPANY (US) | 1992-04-01 | — | — | EP | disclosed |
| EP-0289669-A1 | Process for preparing 3-phenoxybenzaldehydes | HARDWICKE CHEMICAL COMPANY (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0289669-A1 | Process for preparing 3-phenoxybenzaldehydes | HARDWICKE CHEMICAL COMPANY (US) | 1988-11-09 | — | — | EP | disclosed |
| US-4691033-A | Process for preparing 3-phenoxybenzaldehydes | HARDWICKE CHEMICAL COMPANY (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0052836-A1 | Phenoxybenzaldehydes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-02 | — | — | EP | disclosed |