SCHEMBL241692

SCHEMBL241692

OC(c1cccc(Br)c1)c1cccc(Br)c1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.47
TDO2 P48775 1/20 0.47
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42
CYP3A4 P08684 3/20 0.41
CYP2D6 P10635 3/20 0.41
SLC6A2 P23975 3/20 0.41
SLC6A4 P31645 3/20 0.41
SLC6A3 Q01959 3/20 0.41
KCNH2 Q12809 1/20 0.41
C1S P09871 1/20 0.40
PARP1 P09874 1/20 0.40
SLC18A3 Q16572 1/20 0.39
SIGMAR1 Q99720 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31476387 1.00 IDO1 (0.47) IDO1TDO2ALDH1A1MAPK1CYP3A4
SCHEMBL4678 0.93 IDO1 (0.52) IDO1TDO2ALDH1A1SLC18A3SIGMAR1
SCHEMBL3346119 0.88 ACP3 (0.42) IDO1TDO2CYP3A4CYP2D6SLC6A2
SCHEMBL10673316 0.86 CYP3A4 (0.43) IDO1TDO2MAPK1CYP3A4CYP2D6
SCHEMBL8806183 0.86 ALDH1A1 (0.47) IDO1TDO2ALDH1A1MAPK1CYP3A4
SCHEMBL5773097 0.85 CYP3A4 (0.47) IDO1TDO2ALDH1A1MAPK1CYP3A4
SCHEMBL5911692 0.85 CYP3A4 (0.47) IDO1TDO2ALDH1A1MAPK1CYP3A4
SCHEMBL5872085 0.85 IDO1 (0.47) IDO1TDO2ALDH1A1MAPK1CYP3A4
SCHEMBL20139452 0.84 ALDH1A1 (0.40) IDO1TDO2ALDH1A1CYP3A4CYP2D6
SCHEMBL10439663 0.84 MAOB (0.42) IDO1TDO2CYP3A4CYP2D6SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5576417-A Method for synthesizing aromatic polymers DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-11-19 US claimed
US-20250115628-A1 FLUORINATED FLUOROPHORES HOWARD HUGHES MEDICAL INSTITUTE 2025-04-10 US disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
CN-113402462-A Condensed ring compound, preparation method and application thereof, co-host material, light-emitting composition, light-emitting device, lighting device and display device 中国石油化工股份有限公司 2021-09-17 CN disclosed
EP-3438106-A1 ANTI-VIRAL COMPOUNDS AbbVie Ireland Unlimited Company (IE) 2019-02-06 EP disclosed
US-20190015402-A1 Anti-Viral Compounds ABBVIE INC. (US) 2019-01-17 US disclosed
US-10039754-B2 Anti-viral compounds ABBVIE INC. (US) 2018-08-07 US disclosed
US-10028937-B2 Anti-viral compounds ABBVIE INC. (US) 2018-07-24 US disclosed
US-20170157105-A1 Anti-Viral Compounds ABBVIE INC. (US) 2017-06-08 US disclosed
US-20170157104-A1 Anti-Viral Compounds ABBVIE INC. (US) 2017-06-08 US disclosed
EP-2678334-A1 ANTI-VIRAL COMPOUNDS Abbvie Inc. (US) 2014-01-01 EP disclosed
EP-2627651-A1 ANTI-VIRAL COMPOUNDS Abbvie Inc. (US) 2013-08-21 EP disclosed
US-20120220562-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-08-30 US disclosed
WO-2012116257-A1 ANTI-VIRAL COMPOUNDS ABBVIE INC. (US) 2012-08-30 WO disclosed
US-8173696-B2 Inhibitors of cysteine proteases and methods of use thereof BAYLOR UNIVERSITY (US) 2012-05-08 US disclosed
WO-2012051361-A1 ANTI-VIRAL COMPOUNDS ABBOTT LABORATORIES (US) 2012-04-19 WO disclosed
US-20120004196-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-01-05 US disclosed
US-20090076076-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF BAYLOR UNIVERSITY (US) 2009-03-19 US disclosed
US-20060202197-A1 Platinum complex and light-emitting device TAKASAGO INTERNATIONAL CORPORATION 2006-09-14 US disclosed
US-5576417-A Method for synthesizing aromatic polymers DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10028937-B2 Anti-viral compounds HAVCR2, EIF2AK2, MAVS IDO1 2992/4885TDO2 4629/4885ALDH1A1 2858/4885
US-20230285378-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS IDO1 2992/4885TDO2 4629/4885ALDH1A1 2858/4885
US-20120220562-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS IDO1 2992/4885TDO2 4629/4885ALDH1A1 2858/4885
US-20170157105-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS IDO1 2992/4885TDO2 4629/4885ALDH1A1 2858/4885
US-20090076076-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTSB, CTSS, CTSZ IDO1 1605/4885TDO2 1850/4885ALDH1A1 1623/4885
US-20170157104-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS IDO1 2992/4885TDO2 4629/4885ALDH1A1 2858/4885
US-20250115628-A1 FLUORINATED FLUOROPHORES PFAS, FLI1, ARFGEF1 IDO1 3749/4885TDO2 1525/4885ALDH1A1 1109/4885
US-20060202197-A1 Platinum complex and light-emitting device RAD1, RAD51, UACA IDO1 1339/4885TDO2 1064/4885ALDH1A1 1848/4885
US-20190015402-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS IDO1 2992/4885TDO2 4629/4885ALDH1A1 2858/4885
US-20120004196-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS IDO1 2992/4885TDO2 4629/4885ALDH1A1 2858/4885
US-10039754-B2 Anti-viral compounds HAVCR2, EIF2AK2, MAVS IDO1 2992/4885TDO2 4629/4885ALDH1A1 2858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.