Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631695 | 0.78 | CA2 (0.40) | TSHRCA1CA2ALDH1A1HPGD | |
| SCHEMBL7057332 | 0.76 | ALDH1A1 (0.46) | TSHRCA1CA2ALDH1A1TDP1 | |
| SCHEMBL11662121 | 0.76 | MGAM (0.46) | TSHRCA1CA2ALDH1A1USP2 | |
| SCHEMBL462526 | 0.76 | ALDH1A1 (0.40) | TSHRALDH1A1TDP1HTTHPGD | |
| SCHEMBL777517 | 0.76 | TSHR (0.39) | TSHRTDP1HTTHPGD | |
| SCHEMBL5508483 | 0.75 | GRIK1 (0.38) | TSHRCA1CA2ALDH1A1TDP1 | |
| SCHEMBL247701 | 0.75 | CA2 (0.44) | TSHRCA1CA2ALDH1A1TDP1 | |
| SCHEMBL252925 | 0.75 | HTT (0.35) | TSHRALDH1A1HTT | |
| SCHEMBL5508485 | 0.74 | ALDH1A1 (0.47) | TSHRCA1CA2ALDH1A1TDP1 | |
| SCHEMBL776285 | 0.73 | TSHR (0.33) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060153771-A1 | Preparations for measuring gastric emptying ability | OTSUKA PHARMACEUTICAL CO., LTD | 2006-07-13 | — | — | US | disclosed |
| US-7018613-B2 | Safe and easy examination of reduction or acceleration of gastric emptying rate, useful for diagnosis of gastric motor function, and for evaluating pharmacological or therapeutic effects of drugs relating to gastric motor function | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-03-28 | — | — | US | disclosed |
| US-20030190283-A1 | Preparations for evaluating eliminative ability of stomach | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 2003-10-09 | — | — | US | disclosed |
| EP-1285668-A1 | PREPARATIONS FOR EVALUATING ELIMINATIVE ABILITY OF STOMACH | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-02-26 | — | — | EP | disclosed |