SCHEMBL5872295

SCHEMBL5872295

COC(OC)[SiH](C)C1CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8848906 0.78
SCHEMBL8849096 0.76 SHBG (0.32)
SCHEMBL8849199 0.76
SCHEMBL8849019 0.75
SCHEMBL8849231 0.73
SCHEMBL8849182 0.71
SCHEMBL8848870 0.70 CYP1A2 (0.35)
SCHEMBL1901264 0.70 EPHX1 (0.31)
SCHEMBL8849203 0.69 HTT (0.31)
SCHEMBL667444 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0437263-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1995-11-08 EP claimed
US-5106807-A Coordination catalysts comprising a dihydrocarbylethermethyl silane, a titanium halide and a magnesium halide support; stereospecific HIMONT INCORPORATED (US) 1992-04-21 US claimed
EP-0437263-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-07-17 EP claimed
CN-102947352-B Catalyst component for olefin polymerization and catalyst prepared therefrom 巴塞尔聚烯烃股份有限公司 2017-02-22 CN disclosed
CN-102947352-A Catalyst component for olefin polymerization and catalyst prepared therefrom BASELL POLYOLEFINE GMBH 2013-02-27 CN disclosed
US-7022796-B2 Using coordination catalysts FINA TECHNOLOGY, INC. (US) 2006-04-04 US disclosed
US-20040116629-A1 Production of ultra high melt flow polypropylene resins FINA TECHNOLOGY INC. 2004-06-17 US disclosed
US-6657025-B2 Using coordination polymerization catalyst FINA TECHNOLOGY, INC. 2003-12-02 US disclosed
US-20020161139-A1 Production of ultra high melt flow polypropylene resins FINA TECHNOLOGY, INC. 2002-10-31 US disclosed
EP-1223181-A2 Production of ultra high melt flow polypropylene resins FINA TECHNOLOGY, INC. (US) 2002-07-17 EP disclosed
EP-0671417-B1 Components and catalysts for the copolymerisation of olefins MONTELL NORTH AMERICA INC (US) 1997-05-02 EP disclosed
EP-0437263-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1995-11-08 EP disclosed
US-5106807-A Coordination catalysts comprising a dihydrocarbylethermethyl silane, a titanium halide and a magnesium halide support; stereospecific HIMONT INCORPORATED (US) 1992-04-21 US disclosed
EP-0437263-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-07-17 EP disclosed