SCHEMBL8848870

SCHEMBL8848870

CCCCOC(OCCCC)[SiH](C)C1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.32
DNM1 Q05193 1/20 0.32
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8849096 0.81 SHBG (0.32)
SCHEMBL8849231 0.74
SCHEMBL5872295 0.70
SCHEMBL16287272 0.69 SHBG (0.41) CYP1A2SMN1; SMN2NAAA
SCHEMBL16286782 0.69 SHBG (0.41) CYP1A2SMN1; SMN2NAAA
SCHEMBL11851081 0.69 SHBG (0.41) CYP1A2SMN1; SMN2NAAA
SCHEMBL16287712 0.67 SHBG (0.38) CYP1A2SMN1; SMN2DNM1
SCHEMBL27799075 0.67 CYP1A2 (0.37) CYP1A2SMN1; SMN2NAAA
SCHEMBL14472800 0.67 SHBG (0.39) CYP1A2SMN1; SMN2NAAA
SCHEMBL28234075 0.67 SHBG (0.39) CYP1A2SMN1; SMN2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671417-B1 Components and catalysts for the copolymerisation of olefins MONTELL NORTH AMERICA INC (US) 1997-05-02 EP disclosed
EP-0437263-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1995-11-08 EP disclosed
EP-0671417-A2 Components and catalysts for the copolymerisation of olefins MONTELL NORTH AMERICA INC. (US) 1995-09-13 EP disclosed
US-5106807-A Coordination catalysts comprising a dihydrocarbylethermethyl silane, a titanium halide and a magnesium halide support; stereospecific HIMONT INCORPORATED (US) 1992-04-21 US disclosed
EP-0437263-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-07-17 EP disclosed