Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PDE6D | O43924 | 1/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520616 | 0.81 | POLB (1.00) | CYP2C19CYP2C9CYP1A2POLBKDM4E | |
| SCHEMBL23718184 | 0.79 | TSHR (0.84) | CYP2C19CYP2C9POLBKDM4ELMNA | |
| SCHEMBL11766353 | 0.78 | POLB (0.67) | CYP2C19CYP2C9CYP1A2POLBKDM4E | |
| SCHEMBL152719 | 0.76 | TNF (0.65) | CYP2C19CYP2C9CYP1A2LMNAALDH1A1 | |
| SCHEMBL4780057 | 0.75 | CYP2C19 (0.60) | CYP2C19CYP2C9CYP1A2POLBKDM4E | |
| SCHEMBL10583649 | 0.74 | ALDH1A1 (0.97) | CYP2C19CYP2C9CYP1A2POLBKDM4E | |
| SCHEMBL760531 | 0.74 | ALDH1A1 (0.97) | CYP2C19CYP2C9CYP1A2POLBKDM4E | |
| SCHEMBL1169953 | 0.74 | LMNA (0.70) | CYP2C19CYP2C9CYP1A2KDM4ELMNA | |
| SCHEMBL11405502 | 0.73 | CYP2C19 (0.57) | CYP2C19CYP2C9CYP1A2POLBKDM4E | |
| SCHEMBL9673940 | 0.73 | CYP2C19 (0.72) | CYP2C19CYP2C9CYP1A2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112552320-A | One-step in-situ synthesis method of copper-catalyzed N-alkylated benzimidazole derivative and complex | 辽宁石油化工大学 | 2021-03-26 | — | — | CN | disclosed |
| US-7040929-B2 | Surfactants for use in substantially light-insensitive thermographic recording materials | AGFA-GEVAERT (BE) | 2006-05-09 | — | — | US | disclosed |
| US-7015332-B2 | 2-thioalkyl-benzimidazole-5 or 6 sulphonic acids | AGFA GEVAERT (BE) | 2006-03-21 | — | — | US | disclosed |
| US-20050053871-A1 | Novel surfactants for use in substantially light-insensitive thermographic recording materials | AGFA-GEVAERT N.V. (BE) | 2005-03-10 | — | — | US | disclosed |
| US-6780576-B1 | Surfactants | AGFA-GEVAERT (BE) | 2004-08-24 | — | — | US | disclosed |