SCHEMBL5872458

SCHEMBL5872458

CCCCCC=CCC=CCCCCCCCC(=O)C=CCO

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.64
PPARA Q07869 5/20 0.64
ALDH1A1 P00352 5/20 0.63
F7 P08709 4/20 0.63
F3 P13726 4/20 0.63
KDM4E B2RXH2 3/20 0.63
PPARD Q03181 3/20 0.63
FFAR1 O14842 3/20 0.63
FABP3 P05413 2/20 0.63
HPGD P15428 2/20 0.63
PTGS1 P23219 2/20 0.63
DUSP3 P51452 1/20 0.63
PTPN7 P35236 1/20 0.63
LMNA P02545 1/20 0.63
CYP3A4 P08684 1/20 0.63
CYP19A1 P11511 1/20 0.63
FABP4 P15090 1/20 0.63
ALOX15 P16050 1/20 0.63
TSHR P16473 1/20 0.63
GNA15 P30679 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5872449 1.00 PPARG (0.64) PPARGPPARAALDH1A1F7F3
SCHEMBL31511872 0.97 PPARG (0.59) PPARGPPARAALDH1A1F7F3
SCHEMBL31509285 0.92 PPARG (0.70) PPARGPPARAALDH1A1F7F3
SCHEMBL31508786 0.92 PPARG (0.70) PPARGPPARAALDH1A1F7F3
SCHEMBL6473220 0.92 PPARG (0.70) PPARGPPARAALDH1A1F7F3
SCHEMBL8578185 0.92 PPARG (0.70) PPARGPPARAALDH1A1F7F3
SCHEMBL26968801 0.86 PPARG (0.83) PPARGPPARAF7F3KDM4E
SCHEMBL4924633 0.86 PPARG (0.59) PPARGPPARAF7F3KDM4E
SCHEMBL17782010 0.86 PPARG (0.59) PPARGPPARAF7F3KDM4E
SCHEMBL30713149 0.86 PPARG (0.82) PPARGPPARAALDH1A1F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4520348-A1 CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF Sunforest (Beijing) Biopharma Ltd (CN) 2025-03-12 EP disclosed
CN-115607677-A Compound for preventing, preventing or treating microbial infection and preparation and application thereof 太阳雨林(北京)生物医药有限公司 2023-01-17 CN disclosed
CN-114569726-B Compound for preventing, preventing or treating microbial infection and preparation method and application thereof 太阳雨林(北京)生物医药有限公司 2022-10-28 CN disclosed
CN-114788872-A Compound for preventing, preventing or treating microbial infection and preparation and application thereof 太阳雨林(北京)生物医药有限公司 2022-07-26 CN disclosed
CN-114569726-A Compound for preventing, preventing or treating microbial infection and preparation method and application thereof 太阳雨林(北京)生物医药有限公司 2022-06-03 CN disclosed
US-7101913-B2 Hepatic disorder suppressant KAGOME CO., LTD. (JP) 2006-09-05 US disclosed
US-7081480-B2 Hepatic disorder suppressant KAGOME CO., LTD. (JP) 2006-07-25 US disclosed
US-20050170027-A1 Novel hepatic disorder suppressant ARIMOTO YASUSHI (JP) 2005-08-04 US disclosed
US-20050163877-A1 Novel hepatic disorder suppressant ARIMOTO YASUSHI (JP) 2005-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050163877-A1 Novel hepatic disorder suppressant GYS2, OAT, FABP1 PPARG 2935/4885PPARA 2913/4885ALDH1A1 1021/4885
US-20050170027-A1 Novel hepatic disorder suppressant GYS2, OAT, FABP1 PPARG 2935/4885PPARA 2913/4885ALDH1A1 1021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.