Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10390553 | 0.84 | TYR (0.58) | TYRHSD17B10CYP2A6ALDH5A1ABAT | |
| SCHEMBL10490623 | 0.80 | TYR (0.67) | TYRHSD17B10CYP2A6ALDH5A1ABAT | |
| SCHEMBL6820118 | 0.78 | CYP2A6 (0.44) | TYRHSD17B10CYP2A6ALDH1A1TSHR | |
| SCHEMBL1915552 | 0.78 | TYR (0.64) | TYRHSD17B10CYP2A6ALDH5A1ABAT | |
| SCHEMBL6816701 | 0.77 | TYR (0.45) | TYRHSD17B10CYP2A6ALDH1A1TSHR | |
| SCHEMBL4956384 | 0.76 | CYP2A6 (0.69) | TYRHSD17B10CYP2A6ALDH5A1ABAT | |
| SCHEMBL31171 | 0.76 | CYP2A6 (0.69) | TYRHSD17B10CYP2A6ALDH5A1ABAT | |
| SCHEMBL5075045 | 0.76 | TSHR (0.67) | TSHR | |
| SCHEMBL3819415 | 0.74 | TYR (0.58) | TYRHSD17B10CYP2A6ALDH5A1ABAT | |
| SCHEMBL1264527 | 0.74 | ALDH1A1 (0.58) | TYRALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060862-B2 | Method for the preparation of α,α,α′,α′-tetrachloro-p-xylene with high purity | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2006-06-13 | — | — | US | claimed |
| US-6992231-B2 | reacting terephthaldicarboxaldehyde with a mixture of SOCl2 and dimethylformamide (DMF) to obtain a product mixture containing alpha , alpha , alpha ', alpha '-tetrachloro-p-xylene as a major product and 4-dichloromethyl benzaldehyde | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2006-01-31 | — | — | US | claimed |
| US-20050143607-A1 | METHOD FOR THE PREPARATION OF ALPHA, ALPHA, ALPHA', ALPHA'-TETRACHLORO-P-XYLENE | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2005-06-30 | — | — | US | claimed |
| US-20050143608-A1 | Method for the preparation of alpha, alpha, alpha', alpha' -tetrachloro-p-xylene with high purity | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2005-06-30 | — | — | US | claimed |
| CN-116332718-A | Preparation method of 1, 4-bis (chlorodifluoromethyl) benzene | 苏州亚科科技股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-7060862-B2 | Method for the preparation of α,α,α′,α′-tetrachloro-p-xylene with high purity | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2006-06-13 | — | — | US | disclosed |
| US-7060862-B2 | Method for the preparation of α,α,α′,α′-tetrachloro-p-xylene with high purity | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2006-06-13 | — | — | US | disclosed |
| US-6992231-B2 | reacting terephthaldicarboxaldehyde with a mixture of SOCl2 and dimethylformamide (DMF) to obtain a product mixture containing alpha , alpha , alpha ', alpha '-tetrachloro-p-xylene as a major product and 4-dichloromethyl benzaldehyde | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2006-01-31 | — | — | US | disclosed |
| US-6992231-B2 | reacting terephthaldicarboxaldehyde with a mixture of SOCl2 and dimethylformamide (DMF) to obtain a product mixture containing alpha , alpha , alpha ', alpha '-tetrachloro-p-xylene as a major product and 4-dichloromethyl benzaldehyde | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2006-01-31 | — | — | US | disclosed |
| JP-2005232030-A | METHOD FOR PRODUCING α, α, α', α'-TETRACHLORO-P-XYLENE | KOKUBOBU ZHONGSHAN KAGAKU KENKYUIN | 2005-09-02 | — | — | JP | disclosed |
| JP-2005232029-A | METHOD FOR PRODUCING α, α, α', α'-TETRACHLORO-P-XYLENE | KOKUBOBU ZHONGSHAN KAGAKU KENKYUIN | 2005-09-02 | — | — | JP | disclosed |
| US-20050143607-A1 | METHOD FOR THE PREPARATION OF ALPHA, ALPHA, ALPHA', ALPHA'-TETRACHLORO-P-XYLENE | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2005-06-30 | — | — | US | disclosed |
| US-20050143607-A1 | METHOD FOR THE PREPARATION OF ALPHA, ALPHA, ALPHA', ALPHA'-TETRACHLORO-P-XYLENE | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2005-06-30 | — | — | US | disclosed |
| US-20050143608-A1 | Method for the preparation of alpha, alpha, alpha', alpha' -tetrachloro-p-xylene with high purity | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2005-06-30 | — | — | US | disclosed |
| US-20050143608-A1 | Method for the preparation of alpha, alpha, alpha', alpha' -tetrachloro-p-xylene with high purity | CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) | 2005-06-30 | — | — | US | disclosed |
| US-4297502-A | Aromatic bisazomethines, a method for their preparation, and their use as reactive pigments | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1981-10-27 | — | — | US | disclosed |
| US-4125561-A | Process for production of terephthalic dialdehyde | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143607-A1 | METHOD FOR THE PREPARATION OF ALPHA, ALPHA, ALPHA', ALPHA'-TETRACHLORO-P-XYLENE | DDT, B2M, DAGLA | TYR 293/4885HSD17B10 4487/4885CYP2A6 1777/4885 |
| US-20050143608-A1 | Method for the preparation of alpha, alpha, alpha', alpha' -tetrachloro-p-xylene with high purity | DDT, MSMO1, B2M | TYR 43/4885HSD17B10 3905/4885CYP2A6 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.