SCHEMBL1915552

SCHEMBL1915552

O=Cc1ccc(C(c2ccc(C=O)cc2)c2ccc(C=O)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.64
CYP2A6 P11509 4/20 0.50
HSD17B10 Q99714 1/20 0.50
ALDH5A1 P51649 1/20 0.50
ABAT P80404 1/20 0.50
ALDH1A1 P00352 7/20 0.48
ALDH1A3 P47895 2/20 0.44
KDM4E B2RXH2 2/20 0.44
CYP2A13 Q16696 1/20 0.44
ALDH3A1 P30838 1/20 0.41
DRD1 P21728 1/20 0.40
EGFR P00533 1/20 0.39
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39
PTGS2 P35354 1/20 0.39
RAB9A P51151 1/20 0.39
STS P08842 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3697863 0.90 ALDH1A1 (0.59) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL9883870 0.90 ALDH1A1 (0.59) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL2759071 0.88 HSD17B10 (0.73) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL14340735 0.88 CYP2A6 (0.73) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL15043306 0.82 TYR (0.47) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL13701347 0.82 ALDH1A1 (0.76) TYRCYP2A6ALDH1A1ALDH1A3KDM4E
SCHEMBL3696419 0.82 TYR (0.69) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL3693965 0.82 CYP2A6 (0.52) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL18286653 0.81 TYR (0.50) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL31171 0.80 CYP2A6 (0.69) TYRCYP2A6HSD17B10ALDH5A1ABAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328236-B2 Polysiloxane modified resol resin, moulded bodies and composites obtained therefrom and methods for producing the resin, the moulded bodies and the composites FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2016-05-03 US claimed
US-20140275373-A1 POLYSILOXANE MODIFIED RESOL RESIN, MOULDED BODIES AND COMPOSITES OBTAINED THEREFROM AND METHODS FOR PRODUCING THE RESIN, THE MOULDED BODIES AND THE COMPOSITES FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2014-09-18 US claimed
EP-2731992-A1 POLYSILOXANE MODIFIED RESOL RESIN, MOULDED BODIES AND COMPOSITES OBTAINED THEREFROM AND METHODS FOR PRODUCING THE RESIN, THE MOULDED BODIES AND THE COMPOSITES Fraunhofer Gesellschaft zur Förderung der angewandten Forschung E.V. (DE) 2014-05-21 EP claimed
WO-2013007600-A1 POLYSILOXANE MODIFIED RESOL RESIN, MOULDED BODIES AND COMPOSITES OBTAINED THEREFROM AND METHODS FOR PRODUCING THE RESIN, THE MOULDED BODIES AND THE COMPOSITES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2013-01-17 WO claimed
EP-2731992-B1 POLYSILOXANE MODIFIED RESOL RESIN, MOULDED BODIES AND COMPOSITES OBTAINED THEREFROM AND METHODS FOR PRODUCING THE RESIN, THE MOULDED BODIES AND THE COMPOSITES FRAUNHOFER GES FORSCHUNG (DE) 2017-04-12 EP disclosed
US-9328236-B2 Polysiloxane modified resol resin, moulded bodies and composites obtained therefrom and methods for producing the resin, the moulded bodies and the composites FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2016-05-03 US disclosed
US-20140275373-A1 POLYSILOXANE MODIFIED RESOL RESIN, MOULDED BODIES AND COMPOSITES OBTAINED THEREFROM AND METHODS FOR PRODUCING THE RESIN, THE MOULDED BODIES AND THE COMPOSITES FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2014-09-18 US disclosed
EP-2731992-A1 POLYSILOXANE MODIFIED RESOL RESIN, MOULDED BODIES AND COMPOSITES OBTAINED THEREFROM AND METHODS FOR PRODUCING THE RESIN, THE MOULDED BODIES AND THE COMPOSITES Fraunhofer Gesellschaft zur Förderung der angewandten Forschung E.V. (DE) 2014-05-21 EP disclosed
WO-2013007600-A1 POLYSILOXANE MODIFIED RESOL RESIN, MOULDED BODIES AND COMPOSITES OBTAINED THEREFROM AND METHODS FOR PRODUCING THE RESIN, THE MOULDED BODIES AND THE COMPOSITES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2013-01-17 WO disclosed
US-20130018140-A1 N-BRIDGED POLYNITRONS AND THE USE THEREOF AS CROSS-LINKING AGENTS, IN PARTICULAR IN COATING MATERIALS AND ADHESIVES DICKMEIS MARCUS (DE) 2013-01-17 US disclosed
EP-2516531-A1 N-BRIDGED POLYNITRONS AND THE USE THEREOF AS CROSS-LINKERS, IN PARTICULAR IN COATING MATERIALS AND ADHESIVES Dickmeis, Marcus (DE) 2012-10-31 EP disclosed
EP-2516532-A2 POLYOXAZIRIDINES AND USE THEREOF AS A CROSS-LINKING AGENT, ESPECIALLY IN COATING MATERIALS AND ADHESIVES Dickmeis, Marcus (DE) 2012-10-31 EP disclosed
WO-2011085793-A2 POLYOXAZIRIDINES AND USE THEREOF AS A CROSS-LINKING AGENT, ESPECIALLY IN COATING MATERIALS AND ADHESIVES DICKMEIS MARCUS (DE) 2011-07-21 WO disclosed
WO-2011076392-A1 N-BRIDGED POLYNITRONS AND THE USE THEREOF AS CROSS-LINKERS, IN PARTICULAR IN COATING MATERIALS AND ADHESIVES DICKMEIS MARCUS (DE) 2011-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130018140-A1 N-BRIDGED POLYNITRONS AND THE USE THEREOF AS CROSS-LINKING AGENTS, IN PARTICULAR IN COATING MATERIALS AND ADHESIVES PNN, PARN, NCLN TYR 404/4885CYP2A6 3175/4885HSD17B10 4400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.