Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL967172 | 0.82 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL397901 | 0.82 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL31414079 | 0.82 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL820471 | 0.82 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6909569 | 0.80 | PDCD1 (0.36) | PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL31414078 | 0.79 | ADRA2A (0.31) | — | |
| Hydrochloric Acid SCHEMBL6910470 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL5612589 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6056165 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL3163965 | 0.76 | PDCD1 (0.35) | PDCD1CD274CHRNB2CHRNA4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105608-B2 | Copolymer of propylene with a conjugated diene and a process of preparing the same | TONEN CHEMICAL CORPORATION (JP) | 2006-09-12 | — | — | US | disclosed |
| US-20050154139-A1 | Copolymer of propylene with a conjugated diene and a process of preparing the same | TONEN CHEMICAL CORPORATION (JP) | 2005-07-14 | — | — | US | disclosed |
| US-6790917-B2 | POLYMERIZING A VINYL COMPOUND IN PRESENCE OF A CATALYST OBTAINED BY COMBINING ORGANOTRANSITION METAL COMPOUND, AN ALUMINUM COMPUND OR ALUMOXANE AND A BORON COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020198340-A1 | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-26 | — | — | US | disclosed |