SCHEMBL5872681

SCHEMBL5872681

CC=[Zr](Cl)(Cl)(C1C=Cc2c(-c3ccccc3)cccc21)C1C=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5872670 0.81 CYP2A6 (0.32) CHRNB2CHRNA4CYP2A6
SCHEMBL8856002 0.80 CHRNB2 (0.33) CHRNB2CHRNA4CYP2A6
SCHEMBL627681 0.80 CHRNB2 (0.30) CHRNB2CHRNA4CYP2A6
SCHEMBL665513 0.80 CHRNB2 (0.30) CHRNB2CHRNA4CYP2A6
SCHEMBL2781706 0.79
SCHEMBL7203993 0.78 CHRNB2 (0.32) CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL665514 0.77 CHRNB2 (0.31) CHRNB2CHRNA4
SCHEMBL8855996 0.76 TDP1 (0.30)
SCHEMBL7641883 0.75
SCHEMBL20604201 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7105608-B2 Copolymer of propylene with a conjugated diene and a process of preparing the same TONEN CHEMICAL CORPORATION (JP) 2006-09-12 US disclosed
US-20050154139-A1 Copolymer of propylene with a conjugated diene and a process of preparing the same TONEN CHEMICAL CORPORATION (JP) 2005-07-14 US disclosed
US-6825280-B1 RIGIDITY, NONWARPING, NONBLEEDING, ANTISTATIC AGENTS, WEATHERPROOF, IMPACT STRENGTH; OXIDATION AND HEAT RESISTANCE JAPAN POLYCHEM CORPORATION (JP) 2004-11-30 US disclosed
EP-0962474-B1 Propylene block copolymer and resin composition JAPAN POLYCHEM CORP (JP) 2004-04-07 EP disclosed
US-6469100-B2 COORDINATION CATALYST JAPAN POLYCHEM CORPORATION (JP) 2002-10-22 US disclosed
US-20010014719-A1 PROPYLENE BLOCK COPOLYMER AND RESIN COMPOSITION JAPAN POLYCHEM CORPORATION (JP) 2001-08-16 US disclosed
EP-1002814-A1 PROPYLENE BLOCK COPOLYMER AND PROPYLENE RESIN COMPOSITION Japan Polychem Corporation (JP) 2000-05-24 EP disclosed
EP-0962474-A1 Propylene block copolymer and resin composition Japan Polychem Corporation (JP) 1999-12-08 EP disclosed