SCHEMBL665513

SCHEMBL665513

C[SiH](C)[Zr](Cl)(Cl)(C1C=Cc2c(-c3ccccc3)cccc21)C1C=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8606404 0.85
SCHEMBL674147 0.82 MAPT (0.31)
SCHEMBL5872670 0.81 CYP2A6 (0.32) CHRNB2CHRNA4CYP2A6
SCHEMBL7565970 0.80 ADRA1A (0.33)
SCHEMBL8856002 0.80 CHRNB2 (0.33) CHRNB2CHRNA4CYP2A6
SCHEMBL627681 0.80 CHRNB2 (0.30) CHRNB2CHRNA4CYP2A6
SCHEMBL5872681 0.80 CHRNB2 (0.30) CHRNB2CHRNA4CYP2A6
SCHEMBL7205638 0.79
SCHEMBL7191929 0.78
SCHEMBL7197776 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351698-B2 Blend for use in automobile application TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2019-07-16 US claimed
US-9434835-B2 Blend for use in automobile application TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2016-09-06 US claimed
US-12281219-B2 Polypropylene compositions TOTALENERGIES ONETECH BELGIUM (BE) 2025-04-22 US disclosed
US-11859316-B2 Process for the production of fibers TOTALENERGIES ONETECH BELGIUM (BE) 2024-01-02 US disclosed
US-20230323101-A1 POLYPROPYLENE COMPOSITIONS TOTALENERGIES ONETECH BELGIUM (BE) 2023-10-12 US disclosed
EP-4229132-A1 POLYPROPYLENE COMPOSITIONS TotalEnergies OneTech Belgium (BE) 2023-08-23 EP disclosed
US-20220186009-A1 Polypropylene Compositions TOTALENERGIES ONETECH BELGIUM (BE) 2022-06-16 US disclosed
WO-2022079190-A1 POLYPROPYLENE COMPOSITIONS TOTALENERGIES ONE TECH BELGIUM (BE) 2022-04-21 WO disclosed
EP-3953399-A1 POLYPROPYLENE COMPOSITIONS Total Research & Technology Feluy (BE) 2022-02-16 EP disclosed
US-11208510-B2 High purity polypropylenes and polypropylene compositions for molding TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2021-12-28 US disclosed
EP-3912956-A1 POLYETHYLENE-BASED MASTERBATCHES COMPRISING CARBON NANOTUBES AND METALLIC STEARATE FOR PREPARING CONDUCTIVE ARTICLES, PROCESS AND CONDUCTIVE ARTICLES PRODUCED THEREFROM Total Research & Technology Feluy (BE) 2021-11-24 EP disclosed
US-5786432-A POLYMERIZING OR COPOLYMERIZING OLEFIN IN PRESENCE OF TRANSITION METAL METALLOCENE CATALYST AND COCATALYST TARGOR GMBH (DE) 1998-07-28 US disclosed
US-5770753-A ADDITION POLYMERIZATION CATALYST TARGOR GMBH (DE) 1998-06-23 US disclosed
US-5723640-A Transition metal compound having indenyl-containing metallocene MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-03 US disclosed
US-5710223-A COORDINATION POLYMERIZATION CATALYSTS FOR PROPYLENE HOMOPOLYMERS AND COPOLYMERS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1998-01-20 US disclosed
US-5705584-A COORDINATION CATALYSTS FOR ADDITION POLYMERIZATION OF PROPYLENE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-01-06 US disclosed
EP-0812854-A2 Novel transition metal compound, olefin polymerization catalyst comprising said compound, process for olefin polymerization using said catalyst and propylene homo- and copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-12-17 EP disclosed
US-5658997-A USING ZIRCONIUM COMPOUND WITH ALUMINOXANE AND ORGANOALUMINUM COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-08-19 US disclosed
US-5629254-A Substituted indenyl ring containing metallocene catalyst for propylene polymerization process MITSUI PETROCHEMICAL INDUSTRIES CO., LTD. (JP) 1997-05-13 US disclosed
EP-0629632-A2 Novel transition metal compound for use as a polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-12-21 EP disclosed