SCHEMBL5873009

SCHEMBL5873009

Cc1cc(CSCCO)c(O)c(CSCCO)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.56
CYP1A2 P05177 1/20 0.56
BCHE P06276 1/20 0.47
AMY1A P0DUB6 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 2/20 0.39
HSPA5 P11021 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
SELL P14151 1/20 0.34
SELP P16109 1/20 0.34
SELE P16581 1/20 0.34
NPC1 O15118 1/20 0.33
ADORA2A P29274 1/20 0.33
RAB9A P51151 1/20 0.33
CYP2D6 P10635 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 2/20 0.31
CA2 P00918 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10688054 0.82 CYP1A2 (0.58) CYP2C9CYP1A2BCHETDP1
SCHEMBL8990202 0.81 BCHE (0.45) CYP2C9CYP1A2BCHEAMY1ASMN1; SMN2
SCHEMBL8990183 0.79 AMY1A (0.42) CYP2C9CYP1A2BCHEAMY1ASMN1; SMN2
SCHEMBL7563496 0.78 TYR (0.43) CYP2C9CYP1A2BCHEAMY1ASMN1; SMN2
SCHEMBL5086176 0.78 CYP1A2 (0.50) CYP2C9CYP1A2BCHETDP1CA2
SCHEMBL5873065 0.78 TYR (0.43) CYP2C9CYP1A2BCHEAMY1ASMN1; SMN2
SCHEMBL38659961 0.75 POLB (0.41) CYP2C9CYP1A2SMN1; SMN2TDP1NPC1
SCHEMBL5873128 0.74 CYP2C9 (0.39) CYP2C9CYP1A2BCHEAMY1ASMN1; SMN2
SCHEMBL12574913 0.74 ABL1 (0.45) BCHESMN1; SMN2TDP1HSD17B10ALDH1A1
SCHEMBL38660409 0.73 CYP1A2 (0.41) CYP2C9CYP1A2SMN1; SMN2TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9111272-A None JP disclosed
US-7056967-B2 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-06-06 US disclosed
EP-1326915-B1 POLYOLEFIN ARTICLES WITH LONG-TERM ELEVATED TEMPERATURE STABILITY CLARIANT FINANCE BVI LTD (VG) 2005-11-09 EP disclosed
US-6774170-B2 HEAT STABILIZING WITH AN OXIDIZED, NON-CATIONIZED, NON-SILYLATED SULFUR BLACK PIGMENT, A HINDERED PHENOLIC ANTIOXIDANT A SULFUR-CONTAINING SECONDARY STABILIZER, AND A HINDERED AMINE CLARIANT FINANCE (BVI) LIMITED (VG) 2004-08-10 US disclosed
EP-1326915-A2 POLYOLEFIN ARTICLES WITH LONG-TERM ELEVATED TEMPERATURE STABILITY Clariant Finance (BVI) Limited (VG) 2003-07-16 EP disclosed
US-6538056-B1 Polyethylene or polypropylene compounded with sulfur black pigment; sterically hindered phenolic antioxidant and sulfur compound stabilizer; heat resistance CLARIANT INTERNATIONAL LTD. (CH) 2003-03-25 US disclosed
US-20020198344-A1 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
US-20020156165-A1 Polyolefin articles with long-term elevated temperature stability CLARIANT INTERNATIONAL LTD. 2002-10-24 US disclosed
EP-1249845-A2 Stabilized medium and high voltage cable insulation composition Ciba SC Holding AG (CH) 2002-10-16 EP disclosed
WO-2002031043-A2 POLYOLEFIN ARTICLES WITH LONG-TERM ELEVATED TEMPERATURE STABILITY CLARIANT FINANCE (BVI) LIMITED (VG) 2002-04-18 WO disclosed
JP-H09111272-A LUBRICANT COMPOSITION CIBA GEIGY AG 1997-04-28 JP disclosed
US-5427701-A Heat and oxidation resistance, photostability CIBA-GEIGY CORPORATION (US) 1995-06-27 US disclosed
US-5376290-A For elastomers; heat and oxidation resistance, photostability CIBA-GEIGY CORPORATION (US) 1994-12-27 US disclosed
US-5008459-A For elastomers; registance to heat aging CIBA-GEIGY CORPORATION (US) 1991-04-16 US disclosed
EP-0273013-A1 Substituted phenols as stabilizers CIBA-GEIGY AG (CH) 1988-06-29 EP disclosed