Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685150 | 1.00 | ESRRB (0.39) | ESRRBKMT2AALDH1A1THRBCYP2C9 | |
| SCHEMBL5685142 | 1.00 | ESRRB (0.39) | ESRRBKMT2AALDH1A1THRBCYP2C9 | |
| SCHEMBL4706102 | 0.87 | APAF1 (0.37) | ALDH1A1CYP2C19SMN1; SMN2CYP3A4HTT | |
| SCHEMBL4706098 | 0.87 | APAF1 (0.37) | ALDH1A1CYP2C19SMN1; SMN2CYP3A4HTT | |
| SCHEMBL451543 | 0.87 | APAF1 (0.37) | ALDH1A1CYP2C19SMN1; SMN2CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL4708235 | 0.87 | APAF1 (0.37) | ALDH1A1CYP2C19SMN1; SMN2CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL4708232 | 0.87 | APAF1 (0.37) | ALDH1A1CYP2C19SMN1; SMN2CYP3A4HTT | |
| SCHEMBL7898284 | 0.86 | KMT2A (0.39) | KMT2AALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6633064 | 0.85 | CYP3A4 (0.35) | ALDH1A1HPGDSMN1; SMN2CYP3A4HTT | |
| SCHEMBL6636609 | 0.85 | CYP3A4 (0.35) | ALDH1A1HPGDSMN1; SMN2CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129763-A1 | MODULATORS OF TNF-α ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| CN-114644627-B | AhR inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-115698005-B | Fused ring AhR inhibitors | 山东轩竹医药科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2022127753-A1 | FUSED RING AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-06-23 | — | — | WO | disclosed |
| CN-114644627-A | AhR inhibitor and application thereof | 山东轩竹医药科技有限公司 | 2022-06-21 | — | — | CN | disclosed |
| US-6982257-B1 | Vitamin D3 derivative and its production method | TEIJIN LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |