Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685150 | 1.00 | ESRRB (0.39) | ESRRBKMT2AALDH1A1THRBCYP2C9 | |
| SCHEMBL5873084 | 1.00 | ESRRB (0.39) | ESRRBKMT2AALDH1A1THRBCYP2C9 | |
| SCHEMBL4706102 | 0.87 | APAF1 (0.37) | ALDH1A1CYP2C19SMN1; SMN2CYP3A4HTT | |
| SCHEMBL4706098 | 0.87 | APAF1 (0.37) | ALDH1A1CYP2C19SMN1; SMN2CYP3A4HTT | |
| SCHEMBL451543 | 0.87 | APAF1 (0.37) | ALDH1A1CYP2C19SMN1; SMN2CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL4708235 | 0.87 | APAF1 (0.37) | ALDH1A1CYP2C19SMN1; SMN2CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL4708232 | 0.87 | APAF1 (0.37) | ALDH1A1CYP2C19SMN1; SMN2CYP3A4HTT | |
| SCHEMBL7898284 | 0.86 | KMT2A (0.39) | KMT2AALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6633064 | 0.85 | CYP3A4 (0.35) | ALDH1A1HPGDSMN1; SMN2CYP3A4HTT | |
| SCHEMBL6636609 | 0.85 | CYP3A4 (0.35) | ALDH1A1HPGDSMN1; SMN2CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122011012-A | (S) -tert-butyl ((2-methyl-7- (trimethylsilyl) hept-6-alkyne-1-yl) oxy) diphenyl silane and synthesis method and application thereof | 山东省农业科学院 | 2026-05-12 | — | — | CN | disclosed |
| WO-2024129763-A1 | MODULATORS OF TNF-α ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| US-9181152-B2 | Process for preparation of (3R)-2,4-di-leaving group-3-methylbut-1-ene | ALPHORA RESEARCH INC. (CA) | 2015-11-10 | — | — | US | disclosed |
| US-9090623-B2 | Compound JK12A and preparation thereof | LIANYUNGANG JINKANG HEXIN PHARMACEUTICAL CO., LTD. (CN) | 2015-07-28 | — | — | US | disclosed |
| US-20150065708-A1 | COMPOUND JK12A AND PREPARATION THEREOF | LIANYUNGANG JINKANG HEXIN PHARMACEUTICAL CO., LTD. (CN) | 2015-03-05 | — | — | US | disclosed |
| US-20140323744-A1 | PROCESS FOR PREPARATION OF (3R)-2,4-DI-LEAVING GROUP-3-METHYLBUT-1-ENE | ALPHORA RESEARCH INC. (CA) | 2014-10-30 | — | — | US | disclosed |
| WO-2008080986-A1 | FURAN DERIVATIVES, METHOD OF SYNTHESIS AND USES THEREOF | NEUROPHARMA, S.A. (ES) | 2008-07-10 | — | — | WO | disclosed |
| EP-1939191-A1 | Furan derivatives, method of synthesis and uses thereof | Neuropharma S.A. (ES) | 2008-07-02 | — | — | EP | disclosed |
| US-20060223795-A1 | Novel diazabicyclononene derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2006-10-05 | — | — | US | disclosed |
| EP-1622564-A2 | DIAZABICYCLONONENE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004096116-A2 | DIAZABICYCLONONENE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2004-11-11 | — | — | WO | disclosed |
| EP-0818447-B1 | 6-(Hydroxymethyl-ethyl)pyridines as HMG-CoA-reductase inhibitors | BAYER HEALTHCARE AG (DE) | 2004-05-26 | — | — | EP | disclosed |
| EP-0818447-A1 | 6-(Hydroxymethyl-ethyl)pyridines as HMG-CoA-reductase inhibitors | BAYER AG (DE) | 1998-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065708-A1 | COMPOUND JK12A AND PREPARATION THEREOF | GRIK5, GRIK2, GRIK1 | ESRRB 4737/4885KMT2A 92/4885ALDH1A1 1281/4885 |
| US-20140323744-A1 | PROCESS FOR PREPARATION OF (3R)-2,4-DI-LEAVING GROUP-3-METHYLBUT-1-ENE | ALG8, LSS, GYPA | ESRRB 1022/4885KMT2A 1203/4885ALDH1A1 2746/4885 |
| US-20060223795-A1 | Novel diazabicyclononene derivatives | REN, ACE, ACE2 | ESRRB 3728/4885KMT2A 4406/4885ALDH1A1 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.