Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720943 | 0.88 | MEN1 (0.59) | HPGDKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL5873182 | 0.85 | HPGD (0.65) | HPGDKMT2AMEN1MAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL11587518 | 0.80 | MEN1 (0.94) | HPGDKMT2AMEN1MAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL1704711 | 0.78 | MEN1 (1.00) | HPGDKMT2AMEN1MAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL10356288 | 0.78 | MEN1 (1.00) | HPGDKMT2AMEN1MAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL39582 | 0.78 | MEN1 (1.00) | HPGDKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL5873209 | 0.77 | ALDH1A1 (0.50) | HPGDKMT2AMEN1MAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL531257 | 0.76 | MEN1 (0.94) | HPGDKMT2AMEN1MAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL6598370 | 0.76 | MEN1 (0.94) | HPGDKMT2AMEN1MAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL21597905 | 0.76 | MEN1 (0.94) | HPGDKMT2AMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067702-B2 | Process for preparing vinyl substituted beta-diketones | THE JOHNS HOPKINS UNIVERSITY (US) | 2006-06-27 | — | — | US | disclosed |
| US-20060069288-A1 | Process for preparing vinyl substituted beta-diketones | THE JOHNS HOPKINS UNIVERSITY | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069288-A1 | Process for preparing vinyl substituted beta-diketones | VRK1, VRK2, DEK | HPGD 1787/4885KMT2A 1338/4885MEN1 2957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.