Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.63 |
| ▸ | CTSS | P25774 | 5/20 | 0.63 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873392 | 1.00 | CTSK (0.63) | CTSKCTSSGABRB1GABRB2S1PR3 | |
| SCHEMBL5873431 | 1.00 | CTSK (0.63) | CTSKCTSSGABRB1GABRB2S1PR3 | |
| SCHEMBL264362 | 0.87 | CTSK (0.66) | CTSKCTSSGABRB1GABRB2S1PR3 | |
| SCHEMBL116386 | 0.87 | CTSK (0.66) | CTSKCTSSGABRB1GABRB2S1PR3 | |
| SCHEMBL16171655 | 0.87 | CTSK (0.66) | CTSKCTSSGABRB1GABRB2S1PR3 | |
| SCHEMBL16174111 | 0.87 | CTSK (0.66) | CTSKCTSSGABRB1GABRB2S1PR3 | |
| SCHEMBL525862 | 0.87 | CTSK (0.66) | CTSKCTSSGABRB1GABRB2S1PR3 | |
| SCHEMBL14668300 | 0.86 | CTSK (0.64) | CTSKCTSSGABRB1GABRB2S1PR3 | |
| SCHEMBL18435386 | 0.86 | CTSK (0.64) | CTSKCTSSGABRB1GABRB2S1PR3 | |
| Bromide SCHEMBL8184293 | 0.86 | CTSK (0.64) | CTSKCTSSGABRB1GABRB2S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045360-B2 | Method for analysis of reaction products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-05-16 | — | — | US | disclosed |
| US-20020090728-A1 | Method for analysis of reaction products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-07-11 | — | — | US | disclosed |
| WO-2001057526-A1 | METHOD FOR ANALYSIS OF REACTION PRODUCTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2001-08-09 | — | — | WO | disclosed |