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SCHEMBL525862

SCHEMBL525862

CC(C)(C)OC(=O)N[C@@H](C(=O)O)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 3/20 0.66
▸ CTSS P25774 2/20 0.66
▸ ATM Q13315 3/20 0.52
▸ GABRB1 P18505 1/20 0.48
▸ GABRB2 P47870 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ PPARA Q07869 5/20 0.48
▸ PPARG P37231 4/20 0.48
▸ S1PR3 Q99500 1/20 0.47
▸ ACE P12821 1/20 0.47
▸ PPARD Q03181 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL116386 1.00 CTSK (0.66) CTSKCTSSATMGABRB1GABRB2
SCHEMBL264362 1.00 CTSK (0.66) CTSKCTSSATMGABRB1GABRB2
Hydrochloric Acid SCHEMBL28350663 0.98 CTSK (0.64) CTSKCTSSATMGABRB1GABRB2
Bromide SCHEMBL8184293 0.98 CTSK (0.64) CTSKCTSSATMGABRB1GABRB2
SCHEMBL15671568 0.94 CTSK (0.67) CTSKCTSSATMGABRB1GABRB2
SCHEMBL15671569 0.94 CTSK (0.67) CTSKCTSSATMGABRB1GABRB2
SCHEMBL3759870 0.91 CTSK (0.56) CTSKCTSSATMPPARAPPARG
SCHEMBL27158950 0.91 CTSK (0.56) CTSKCTSSATMPPARAPPARG
SCHEMBL16171655 0.90 CTSK (0.66) CTSKCTSSATMGABRB1GABRB2
SCHEMBL16174111 0.90 CTSK (0.66) CTSKCTSSATMGABRB1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 475 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090036679-A1 METHOD FOR RESOLVING ENANTIOMERS FROM RACEMIC MIXTURE HAVING CHIRAL CARBON IN ALPHA POSITION OF NITROGEN CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2009-02-05 — — US claimed
EP-1984358-A1 METHOD FOR RESOLVING ENANTIOMERS FROM RACEMIC MIXTURE HAVING CHIRAL CARBON IN ALPHA POSITION OF NITROGEN Chong Kun Dang Pharmaceutical Corp. (KR) 2008-10-29 — — EP claimed
WO-2007091753-A1 METHOD FOR RESOLVING ENANTIOMERS FROM RACEMIC MIXTURE HAVING CHIRAL CARBON IN ALPHA POSITION OF NITROGEN CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2007-08-16 — — WO claimed
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS INC (US) 2026-01-01 — — US disclosed
US-20250376443-A1 MASP-2 INHIBITORS AND METHODS OF USE OMEROS CORPORATION (US) 2025-12-11 — — US disclosed
US-20250368604-A1 MASP-2 INHIBITORS AND METHODS OF USE OMEROS CORPORATION (US) 2025-12-04 — — US disclosed
US-20250346616-A1 ROCK INHIBITORS AND USES THEREOF DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) 2025-11-13 — — US disclosed
EP-4551563-A2 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2025-05-14 — — EP disclosed
CN-119930740-A Dipeptide compound, chimeric molecule based on dipeptide compound and application of dipeptide compound 西南交通大学 2025-05-06 — — CN disclosed
US-20250129020-A1 MASP-2 INHIBITORS AND METHODS OF USE OMEROS CORPORATION (US) 2025-04-24 — — US disclosed
CN-119816487-A FC conjugates comprising CD73 inhibitors and uses thereof 奇达拉治疗公司 2025-04-11 — — CN disclosed
WO-2001057526-A1 METHOD FOR ANALYSIS OF REACTION PRODUCTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2001-08-09 — — WO disclosed
US-6201006-B1 ANTICOAGULANTS C & C RESEARCH LABORATORIES (KR) 2001-03-13 — — US disclosed
EP-0604182-B1 Inhibitors of HIV protease useful for the treatment of Aids LILLY CO ELI (US) 2000-10-11 — — EP disclosed
CN-1219932-A Aromatic amidine derivatives useful as selective thrombin inhibitors C & C RESEARCH LAB (KR) 1999-06-16 — — CN disclosed
EP-0918768-A1 AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS C & C Research Laboratories (KR) 1999-06-02 — — EP disclosed
WO-1997045424-A1 AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS C & C RESEARCH LABORATORIES (KR) 1997-12-04 — — WO disclosed
CN-1034504-C Thioalkylthio cephalosporin derivatives SHIONOGI & CO (JP) 1997-04-09 — — CN disclosed
US-5502061-A ENZYME INHIBITORS FOR HIV FOR TREATMENT OR PREVENTION OF AIDS ELI LILLY AND COMPANY (US) 1996-03-26 — — US disclosed
EP-0604182-A2 Inhibitors of HIV protease useful for the treatment of Aids ELI LILLY AND COMPANY (US) 1994-06-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346616-A1 ROCK INHIBITORS AND USES THEREOF ROCK1, ROCK2, RHOA CTSK 1192/4885CTSS 2671/4885ATM 1532/4885
US-20250368604-A1 MASP-2 INHIBITORS AND METHODS OF USE MASP2, METAP2, SPINT2 CTSK 485/4885CTSS 439/4885ATM 1956/4885
US-20250376443-A1 MASP-2 INHIBITORS AND METHODS OF USE MASP2, METAP2, SPINT2 CTSK 436/4885CTSS 379/4885ATM 2049/4885
US-20090036679-A1 METHOD FOR RESOLVING ENANTIOMERS FROM RACEMIC MIXTURE HAVING CHIRAL CARBON IN ALPHA POSITION OF NITROGEN SRR, NPEPPS, DNPEP CTSK 2431/4885CTSS 898/4885ATM 4636/4885
US-20250129020-A1 MASP-2 INHIBITORS AND METHODS OF USE MASP2, METAP2, SPINT2 CTSK 485/4885CTSS 439/4885ATM 1956/4885
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF FCGR2A, FCGR1A, FCGR3B CTSK 2406/4885CTSS 1555/4885ATM 4379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.