SCHEMBL5873410

SCHEMBL5873410

O=C(O)C=NOCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.49
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
KMT2A Q03164 3/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 2/20 0.46
ALDH1A1 P00352 6/20 0.46
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 1/20 0.43
PKM P14618 1/20 0.43
NAMPT P43490 1/20 0.43
CA12 O43570 1/20 0.42
AKR1B10 O60218 1/20 0.42
AKR1B1 P15121 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10746742 1.00 HCAR2 (0.49) HCAR2PPARGPPARAKMT2ANPC1
SCHEMBL7072590 1.00 HCAR2 (0.49) HCAR2PPARGPPARAKMT2ANPC1
SCHEMBL20398954 0.85 ALDH1A1 (0.52) HCAR2PPARGPPARAKMT2ANPC1
SCHEMBL9899924 0.85 ALDH1A1 (0.52) HCAR2PPARGPPARAKMT2ANPC1
SCHEMBL20398955 0.85 ALDH1A1 (0.52) HCAR2PPARGPPARAKMT2ANPC1
SCHEMBL9899925 0.85 ALDH1A1 (0.52) HCAR2PPARGPPARAKMT2ANPC1
SCHEMBL20414342 0.85 ALDH1A1 (0.52) HCAR2PPARGPPARAKMT2ANPC1
SCHEMBL408179 0.85 PPARG (0.48) HCAR2PPARGPPARAKMT2ANPC1
SCHEMBL408180 0.85 PPARG (0.48) HCAR2PPARGPPARAKMT2ANPC1
SCHEMBL16739282 0.84 L3MBTL1 (0.48) KMT2ANPC1RAB9AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4591121-A1 USE OF A METAL AND/OR METALLOID-COMPRISING KETOACIDOXIMATE AND/OR A METAL-COMPOUND-COMPRISING KETOACIDOXIMATE AS A PATTERNING AGENT PAUL SCHERRER INSTITUT (CH) 2025-07-30 EP disclosed
WO-2024061550-A1 USE OF A METAL AND/OR METALLOID-COMPRISING KETOACIDOXIMATE AND/OR A METAL-COMPOUND-COMPRISING KETOACIDOXIMATE AS A PATTERNING AGENT PAUL SCHERRER INSTITUT (CH) 2024-03-28 WO disclosed
US-7045360-B2 Method for analysis of reaction products PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2006-05-16 US disclosed
US-20020090728-A1 Method for analysis of reaction products PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2002-07-11 US disclosed
WO-2001057526-A1 METHOD FOR ANALYSIS OF REACTION PRODUCTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2001-08-09 WO disclosed
US-5606095-A 2-aminooxymethylenephenylacetic acid derivatives CIBA-GEIGY CORPORATION (US) 1997-02-25 US disclosed
EP-0600835-B1 Method for the production of derivatives of phenylacetic acid esters CIBA GEIGY AG (CH) 1996-09-11 EP disclosed
EP-0600835-A1 Method for the production of derivatives of phenylacetic acid esters CIBA-GEIGY AG (CH) 1994-06-08 EP disclosed
US-4698338-A ANTIBIOTICS ELI LILLY AND COMPANY (US) 1987-10-06 US disclosed
EP-0233780-A2 O-substituted oximino cephalosporins ELI LILLY AND COMPANY (US) 1987-08-26 EP disclosed