SCHEMBL5873466

SCHEMBL5873466

OC(C1=CCC(F)(F)C=C1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
ALDH1A1 P00352 1/20 0.30
AOC3 Q16853 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7692973 0.81 TSHR (0.34) LMNA
SCHEMBL10883785 0.78 MEN1 (0.37) SMN1; SMN2KDM4EALDH1A1AOC3
SCHEMBL29776330 0.76 CYP2C9 (0.34) LMNASMN1; SMN2KDM4EALDH1A1AOC3
SCHEMBL29136464 0.76 TSHR (0.37) SMN1; SMN2
SCHEMBL28645425 0.74 CNR2 (0.33) KDM4EALDH1A1
SCHEMBL11043854 0.73
SCHEMBL11606767 0.67 AOC3 (0.37) LMNAKDM4EALDH1A1AOC3
SCHEMBL10539359 0.66 SLC6A2 (0.31)
Diphenylmethanol SCHEMBL10868602 0.63 SMN1; SMN2 (0.61) LMNAMAPK1SMN1; SMN2KDM4EL3MBTL1
Diphenylmethanol SCHEMBL6434457 0.63 SMN1; SMN2 (0.61) LMNAMAPK1SMN1; SMN2KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119505045-A Preparation method of high-performance polyethylene/glass fiber composite material and application of high-performance polyethylene/glass fiber composite material in modified polypropylene 安徽大学 2025-02-25 CN claimed
CN-110967421-B Method for detecting related substances of flunarizine hydrochloride preparation 正大青春宝药业有限公司 2022-04-12 CN claimed
CN-110967421-A Method for detecting related substances of flunarizine hydrochloride preparation 正大青春宝药业有限公司 2020-04-07 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
CN-119505045-A Preparation method of high-performance polyethylene/glass fiber composite material and application of high-performance polyethylene/glass fiber composite material in modified polypropylene 安徽大学 2025-02-25 CN disclosed
CN-110967421-B Method for detecting related substances of flunarizine hydrochloride preparation 正大青春宝药业有限公司 2022-04-12 CN disclosed
CN-110967421-B Method for detecting related substances of flunarizine hydrochloride preparation 正大青春宝药业有限公司 2022-04-12 CN disclosed
CN-110967421-A Method for detecting related substances of flunarizine hydrochloride preparation 正大青春宝药业有限公司 2020-04-07 CN disclosed
CN-110967421-A Method for detecting related substances of flunarizine hydrochloride preparation 正大青春宝药业有限公司 2020-04-07 CN disclosed
WO-2005095544-A1 LIQUID CRYSTAL COMPOUNDS, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2005-10-13 WO disclosed