SCHEMBL29136464

SCHEMBL29136464

N#CC1(C#N)C=CC(C(O)c2ccccc2)=CC1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
PGR P06401 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883785 0.77 MEN1 (0.37) SMN1; SMN2
SCHEMBL5873466 0.76 LMNA (0.33) SMN1; SMN2
SCHEMBL29776330 0.73 CYP2C9 (0.34) TSHRSMN1; SMN2
SCHEMBL28645425 0.71 CNR2 (0.33)
SCHEMBL4752223 0.69 NOTUM (0.30)
SCHEMBL5435458 0.67 ALDH1A1 (0.38) SMN1; SMN2
SCHEMBL11606767 0.64 AOC3 (0.37) TSHR
SCHEMBL10539359 0.62 SLC6A2 (0.31) TSHR
Diphenylmethanol SCHEMBL10868602 0.60 SMN1; SMN2 (0.61) TSHRSMN1; SMN2
Diphenylmethanol SCHEMBL41571 0.60 SMN1; SMN2 (0.61) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362162-A Preparation method of carbonyl compound 中国科学院大连化学物理研究所 2024-01-09 CN disclosed