SCHEMBL10539359

SCHEMBL10539359

OC1(O)C=CC(C(c2ccccc2)c2ccccc2)=CC1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
TSHR P16473 1/20 0.31
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28057890 0.92 ALDH1A1 (0.36)
SCHEMBL11606767 0.83 AOC3 (0.37) SLC6A2SLC6A4SLC6A3TSHR
SCHEMBL29120336 0.79 OPRM1 (0.31) SLC6A2SLC6A4SLC6A3OPRM1OPRD1
SCHEMBL28604276 0.72 SRC (0.34)
SCHEMBL1654081 0.72 CYP3A4 (0.33)
SCHEMBL4647750 0.71
SCHEMBL8773523 0.67 HTR2A (0.38) OPRM1OPRD1OPRK1OPRL1
Biphenyl SCHEMBL27559195 0.67 ALDH1A1 (0.35)
SCHEMBL22199538 0.66 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3TSHR
SCHEMBL5873466 0.66 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4837277-A HIGH RESISTANCE TO FOOD STAINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-06-06 US disclosed
EP-0274248-A2 Poly(4-methyl-1-pentene) composition and articles molded therefrom MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-07-13 EP disclosed
US-3959353-A Esters of hydroxyaryl adducts of decachloropentacyclo (5.3.0.02,6.04,10 05,9) decane-3-one HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-05-25 US disclosed