Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000720 | 0.75 | PTGS2 (0.44) | PTGS2CYP2C19CYP3A4HPGDCYP2D6 | |
| SCHEMBL3701250 | 0.74 | PTGS2 (0.52) | PTGS2CYP2C19CYP3A4HPGDCYP2D6 | |
| SCHEMBL999079 | 0.73 | PTGS2 (0.38) | PTGS2CYP2C19CYP3A4HPGDCYP2D6 | |
| SCHEMBL3840548 | 0.73 | PTGS2 (0.47) | PTGS2CYP2C19HPGDDRD3CYP1A2 | |
| SCHEMBL28195583 | 0.72 | PTGS2 (0.40) | PTGS2CYP2C19CYP3A4HPGDCYP2D6 | |
| Lactic Acid SCHEMBL14060787 | 0.71 | TP53 (0.48) | PTGS2MEN1KMT2ALMNATP53 | |
| Methylamine SCHEMBL31352744 | 0.70 | PTGS2 (0.69) | PTGS2CYP2C19CYP3A4HPGDCYP2D6 | |
| SCHEMBL59839 | 0.69 | PTGS2 (0.52) | PTGS2CYP2C19CYP3A4HPGDCYP2D6 | |
| SCHEMBL30338418 | 0.69 | PTGS2 (0.52) | PTGS2CYP2C19CYP3A4HPGDCYP2D6 | |
| SCHEMBL5215577 | 0.69 | PTGS2 (0.52) | PTGS2CYP2C19CYP3A4HPGDCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034174-B2 | Mono-, oligo- and polymers comprising a 2,6-azulene group and their use as charge transport materials | MERCK PATENT GMBH (DE) | 2006-04-25 | — | — | US | disclosed |
| EP-1318183-B1 | Oligomers and Polymers comprising a 2,6-azulene group and their use as charge transport materials | MERCK PATENT GMBH (DE) | 2005-05-18 | — | — | EP | disclosed |
| US-20030122479-A1 | Mono-, oligo- and polymers comprising a 2,6-azulene group and their use as charge transport materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2003-07-03 | — | — | US | disclosed |
| EP-1318183-A1 | Mono,- oligo- and polymers comprising a 2,6-azulene group and their use as charge transport materials | MERCK PATENT GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030122479-A1 | Mono-, oligo- and polymers comprising a 2,6-azulene group and their use as charge transport materials | PARN, PARG, SLCO2A1 | PTGS2 3215/4885CYP2C19 2378/4885CYP3A4 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.