SCHEMBL59839

SCHEMBL59839

CC(C(=O)O)c1ccccc1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 10/20 0.52
CXCL8 P10145 3/20 0.46
MMP2 P08253 2/20 0.46
MMP9 P14780 2/20 0.46
MMP8 P22894 2/20 0.46
MMP12 P39900 2/20 0.46
MMP13 P45452 2/20 0.46
MMP14 P50281 2/20 0.46
MMP16 P51512 2/20 0.46
MMP1 P03956 1/20 0.46
PTGS1 P23219 7/20 0.45
CYP2C9 P11712 3/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 2/20 0.42
HPGD P15428 2/20 0.42
ADRA2C P18825 1/20 0.42
MAOA P21397 1/20 0.42
ADRA1A P35348 1/20 0.42
DRD3 P35462 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5215577 1.00 PTGS2 (0.52) PTGS2CXCL8MMP2MMP9MMP8
SCHEMBL30338418 1.00 PTGS2 (0.52) PTGS2CXCL8MMP2MMP9MMP8
SCHEMBL288752 1.00 PTGS2 (0.52) PTGS2CXCL8MMP2MMP9MMP8
SCHEMBL8203180 0.88 PTGS2 (0.42) PTGS2CXCL8MMP2MMP9MMP8
SCHEMBL27304888 0.85 ALDH1A1 (0.40) PTGS2CXCL8KDM4EALDH1A1CYP3A4
SCHEMBL2204495 0.84 PTGS2 (0.56) PTGS2CXCL8MMP2MMP9MMP8
SCHEMBL1000051 0.84 CXCL8 (0.44) PTGS2CXCL8MMP2MMP9MMP8
SCHEMBL7381015 0.84 CYP3A4 (0.48) PTGS2CXCL8MMP2MMP9MMP8
SCHEMBL250282 0.83 CXCL8 (0.49) PTGS2CXCL8KDM4EALDH1A1CYP3A4
SCHEMBL8664725 0.82 MMP2 (0.48) PTGS2CXCL8MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 448 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118996022-A Organic leather tanning agent with covalent tanning characteristics, and preparation method and application thereof 四川德赛尔新材料科技有限公司 2024-11-22 CN claimed
CN-110707221-B Application of amino acid ionic liquid in preparation of perovskite layer in perovskite photoelectric device 北京大学深圳研究生院 2023-09-01 CN claimed
CN-114456438-B Composite material for enriching viruses in droplets and application thereof 四川大学 2022-11-22 CN claimed
CN-114570178-A Carbon dioxide absorbent and preparation method and application thereof 上海交通大学 2022-06-03 CN claimed
CN-114456438-A Composite material for enriching viruses in droplets and application thereof 四川大学 2022-05-10 CN claimed
EP-3059004-B1 METHOD FOR REMOVING SOX FROM GAS WITH COMPLEX ALCOHOL-AMINE SOLUTION BEIJING BOYUAN HENGSHENG HIGH TECH CO LTD (CN) 2021-06-30 EP claimed
CN-110857454-B Method for recovering lead from lead-containing waste 北京化工大学 2021-04-23 CN claimed
CN-110857454-A Method for recovering lead from lead-containing waste 北京化工大学 2020-03-03 CN claimed
CN-110707221-A Application of amino acid ionic liquid in preparation of perovskite layer in perovskite photoelectric device 北京大学深圳研究生院 2020-01-17 CN claimed
CN-109999017-A The method for treating fibrosis 诺格拉制药有限公司 2019-07-12 CN claimed
US-20160243491-A1 Method for Removing SOx from Gas with Compound Alcohol-Amine Solution PEKING UNIVERSITY (CN) 2016-08-25 US claimed
EP-3059004-A1 METHOD FOR REMOVING SOX FROM GAS WITHNCOMPOUND ALCOHOL-AMINE SOLUTION Beijing Boyuan-Hengsheng High-Technology Co., Ltd. (CN) 2016-08-24 EP claimed
US-8299225-B2 Amidite for synthesizing modified nucleic acid and method for synthesizing modified nucleic acid FUJITSU LIMITED (JP) 2012-10-30 US claimed
US-8129092-B2 Resist pattern thickening material and process for forming resist pattern, and semiconductor device and method for manufacturing the same FUJITSU LIMITED (JP) 2012-03-06 US claimed
CN-1975571-B Resist pattern thickening material and process for forming resist pattern, and semiconductor device and method for manufacturing the same FUJITSU LTD 2011-04-06 CN claimed
US-20090062521-A1 AMIDITE FOR SYNTHESIZING MODIFIED NUCLEIC ACID AND METHOD FOR SYNTHESIZING MODIFIED NUCLEIC ACID FUJITSU LIMITED (JP) 2009-03-05 US claimed
US-20080167459-A1 Amidite for nucleic acid synthesis and nucleic acid synthesizing method FUJITSU LIMITED (JP) 2008-07-10 US claimed
EP-0379423-B1 PROCESS FOR THE PREPARATION OF PHENYLPROPIONIC ACID BOUCHARA S.A. (FR) 1993-06-23 EP claimed
CN-1058206-A Produce the novel method of benzyl propionate derivant BOUCHARA SA (FR) 1992-01-29 CN claimed
EP-0077662-B1 PREPARATION OF NITROARYLACETIC ACID ESTERS AND DERIVATIVES THEREOF ETHYL CORPORATION (US) 1985-10-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167459-A1 Amidite for nucleic acid synthesis and nucleic acid synthesizing method GABBR2, RNGTT, BCAT2 PTGS2 2578/4885CXCL8 4523/4885MMP2 3660/4885
US-20090062521-A1 AMIDITE FOR SYNTHESIZING MODIFIED NUCLEIC ACID AND METHOD FOR SYNTHESIZING MODIFIED NUCLEIC ACID NSUN2, RNMT, ADAR PTGS2 2786/4885CXCL8 3362/4885MMP2 2654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.