Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.32 |
| ▸ | PGK2 | P07205 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873865 | 1.00 | PGK1 (0.32) | PGK1PGK2ENPP2DGAT2 | |
| SCHEMBL5873741 | 0.85 | NPY5R (0.37) | — | |
| SCHEMBL5873744 | 0.85 | NPY5R (0.37) | — | |
| SCHEMBL5873774 | 0.81 | MAPT (0.41) | PGK1PGK2ENPP2DGAT2 | |
| SCHEMBL5873768 | 0.81 | MAPT (0.41) | PGK1PGK2ENPP2DGAT2 | |
| SCHEMBL5873756 | 0.80 | APP (0.33) | — | |
| SCHEMBL5873755 | 0.80 | APP (0.33) | — | |
| SCHEMBL5873956 | 0.77 | NTRK1 (0.41) | PGK1PGK2 | |
| SCHEMBL5171377 | 0.76 | PKM (0.47) | — | |
| SCHEMBL5430391 | 0.76 | PKM (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129253-B2 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-31 | — | — | US | disclosed |
| US-6818632-B2 | 3-(anilinomethylene)oxindoles | SMITHKLINE BEECHAM CORPORATION | 2004-11-16 | — | — | US | disclosed |
| US-6498176-B1 | INHIBITING TUMOR GROWTH VIA INHIBITION OF TUMOR-RELATED ANGIOGENESIS | SMITHKLINEBEECHAM CORPORATION | 2002-12-24 | — | — | US | disclosed |
| US-6350747-B1 | PROTEIN SERINE/THREONINE KINASE AND PROTEIN TYROSINE KINASE ENZYME INHIBITORS; ANGIOGENESIS INHIBITORS; ANTITUMOR AND ANTIPROLIFERATIVE AGENTS | GLAXO WELLCOME INC. | 2002-02-26 | — | — | US | disclosed |