SCHEMBL11380977

SCHEMBL11380977

CC(=O)C(Oc1ccccc1)C(=O)Nc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
MAPT P10636 4/20 0.56
ATM Q13315 2/20 0.56
LMNA P02545 2/20 0.56
GAA P10253 2/20 0.56
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
RXFP1 Q9HBX9 2/20 0.52
POLB P06746 2/20 0.51
TSHR P16473 1/20 0.51
HTT P42858 1/20 0.50
NAPRT Q6XQN6 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TP53 P04637 1/20 0.48
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
MME P08473 1/20 0.45
ACE P12821 1/20 0.45
HSP90AA1 P07900 1/20 0.45
GPR55 Q9Y2T6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL587395 0.83 MAPT (0.59) ALDH1A1MAPTATMLMNAGAA
SCHEMBL1342135 0.82 ATM (0.57) ALDH1A1ATMLMNAGAAMEN1
SCHEMBL13532261 0.79 KMT2A (0.77) ALDH1A1ATMLMNAMEN1KMT2A
SCHEMBL11382012 0.79 MAPT (0.54) ALDH1A1MAPTATMLMNAGAA
SCHEMBL4564099 0.78 LDHA (0.52) ALDH1A1LMNAGAAMEN1KMT2A
SCHEMBL14653107 0.77 KLK7 (0.58) ALDH1A1MAPTATMLMNAGAA
SCHEMBL29988895 0.76 MEN1 (0.54) ALDH1A1MAPTATMLMNAGAA
SCHEMBL5411510 0.75 MTNR1A (0.45) ALDH1A1LMNAGAAMEN1KMT2A
SCHEMBL10966266 0.75 MTNR1A (0.45) ALDH1A1LMNAGAAMEN1KMT2A
SCHEMBL935298 0.74 CYP1A2 (0.68) ALDH1A1MAPTATMLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4305833-A Lubricating oils containing acetoacetanilides as antioxidants UOP INC. (US) 1981-12-15 US disclosed