Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.75 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.75 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.75 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.56 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.53 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.53 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KDM5C | P41229 | 4/20 | 0.53 |
| ▸ | GABRP | O00591 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL5874481 | 1.00 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL9326105 | 0.93 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL27804789 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL27584447 | 0.87 | EGLN1 (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL28156291 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL3628497 | 0.87 | EGLN1 (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL7752977 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL30575212 | 0.87 | EGLN1 (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL28729193 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL1655131 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260027-A | Stress sustained-release agent and preparation method and application thereof | 清华大学 | 2022-11-01 | — | — | CN | claimed |
| WO-2025022017-A1 | HYDROPHOBICALLY MODIFIED STARCH | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2025-01-30 | — | — | WO | disclosed |
| CN-115385845-B | Preparation of pyrrole sulfonic acid compound salt | 江苏柯菲平医药股份有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-115260027-B | Stress sustained release agent and preparation method and application thereof | 清华大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-115385845-A | Preparation of pyrrole sulfonic acid compound salt | 江苏柯菲平医药股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-115260027-A | Stress sustained-release agent and preparation method and application thereof | 清华大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-107814758-B | Preparation of pyrrole sulfonic acid compound salt | 江苏柯菲平医药股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-110312768-A | Ink-jet ink | 惠普发展公司，有限责任合伙企业 | 2019-10-08 | — | — | CN | disclosed |
| CN-108602771-A | The new acid-addition salts of 1- (5- (2,4 difluorobenzene base) -1- ((3- fluorophenyls) sulfonyl) -4- methoxyl group -1H- pyrroles -3- bases)-N- methyl methylamines | 株式会社大熊制药 | 2018-09-28 | — | — | CN | disclosed |
| CN-108602772-A | Novel crystal form of 1- (5- (2, 4-difluorophenyl) -1- ((3-fluorophenyl) sulfonyl) -4-methoxy-1H-pyrrole-3-yl) -N-methylmelamine salt | 株式会社大熊制药 | 2018-09-28 | — | — | CN | disclosed |
| CN-102127337-A | A light-cyan solid ink composition and its preparation method | XEROX CORP | 2011-07-20 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-6262299-B1 | Zwitterionic monomer having amino-multicarboxylic acid functionality | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION | 2001-07-17 | — | — | US | disclosed |
| EP-1067115-A1 | Zwitterionic monomer having aminomulticarboxylic acid functionality | National Starch and Chemical Investment Holding Corporation (US) | 2001-01-10 | — | — | EP | disclosed |
| EP-0666272-B1 | Starches modified with amino-multicarboxylates | NAT STARCH CHEM INVEST (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5500087-A | IMPROVED STRENGTH AND PIGMENT RETENTION | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1996-03-19 | — | — | US | disclosed |
| US-5455340-A | Retention and wet strength aids in papermaking; chelation of copper and calcium compounds | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1995-10-03 | — | — | US | disclosed |
| EP-0666272-A1 | Starches modified with amino-multicarboxylates | National Starch and Chemical Investment Holding Corporation (US) | 1995-08-09 | — | — | EP | disclosed |
| US-3992251-A | Process of making wet strength paper containing mono primary polyamine and organic dihalide modified, epoxidized polyamide | DIAMOND SHAMROCK CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |