Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.56 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.56 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.56 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL5874738 | 0.88 | AKR1B1 (0.62) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Tetrylammonium SCHEMBL5875097 | 0.88 | SLC22A6 (0.61) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL8538097 | 0.88 | AKR1B1 (0.62) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Tetrylammonium SCHEMBL27654310 | 0.88 | FFAR3 (0.72) | LMNAEGLN1ALKBH5SUCNR1FFAR3 | |
| Tetrylammonium SCHEMBL5874617 | 0.87 | FFAR3 (0.46) | LMNAEGLN1ALKBH5SUCNR1FFAR3 | |
| Sebacic Acid SCHEMBL5874755 | 0.86 | GPR84 (0.64) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Azelaic Acid SCHEMBL8029018 | 0.86 | GPR84 (0.64) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Tetrylammonium SCHEMBL27645685 | 0.84 | FFAR3 (0.67) | LMNAFFAR3HDAC3HDAC1HDAC2 | |
| Tetrylammonium SCHEMBL5574995 | 0.84 | AKR1B1 (0.64) | LMNAFFAR3HDAC3HDAC1HDAC2 | |
| Tetrylammonium SCHEMBL168441 | 0.83 | TSHR (0.61) | LMNAFFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4885115-A | Liquid electrolyte for use in electrolytic capacitor | NIPPON CHEMI-CON CORPORATION (JP) | 1989-12-05 | — | — | US | claimed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-4885115-A | Liquid electrolyte for use in electrolytic capacitor | NIPPON CHEMI-CON CORPORATION (JP) | 1989-12-05 | — | — | US | disclosed |