Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.86 |
| ▸ | HPGD | P15428 | 8/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.86 |
| ▸ | CA12 | O43570 | 1/20 | 0.86 |
| ▸ | CA1 | P00915 | 1/20 | 0.86 |
| ▸ | CA2 | P00918 | 1/20 | 0.86 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.86 |
| ▸ | CA4 | P22748 | 1/20 | 0.86 |
| ▸ | CA6 | P23280 | 1/20 | 0.86 |
| ▸ | CA7 | P43166 | 1/20 | 0.86 |
| ▸ | CA9 | Q16790 | 1/20 | 0.86 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.86 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.86 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CASP7 | P55210 | 2/20 | 0.59 |
| ▸ | G6PD | P11413 | 1/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL8029424 | 0.93 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29555395 | 0.93 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL27499117 | 0.93 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29110644 | 0.93 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29362663 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1967 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1509155 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29606432 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29360246 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL8433746 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-5260475-A | Esterification of hydroxybenzoic acids | RHONE-POULENC CHIMIE (FR) | 1993-11-09 | — | — | US | disclosed |
| US-5001156-A | Lipophilic quaternary ammonium salicylates, their use in cosmetics and in dermopharmacy | L'OREAL (FR) | 1991-03-19 | — | — | US | disclosed |
| US-4529398-A | Method for preventing contamination of catheter and drainage receptacle | BUDDY L (HONG KONG), LTD., A CORP. OF HONG KONG | 1985-07-16 | — | — | US | disclosed |