Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 4/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | FABP3 | P05413 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL8028982 | 0.97 | BBOX1 (0.56) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Azelaic Acid SCHEMBL8778169 | 0.97 | BBOX1 (0.56) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Sebacic Acid SCHEMBL5874751 | 0.97 | BBOX1 (0.56) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Azelaic Acid SCHEMBL8029012 | 0.95 | BBOX1 (0.54) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Tetrylammonium SCHEMBL5875094 | 0.95 | BBOX1 (0.58) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Tetrylammonium SCHEMBL5571730 | 0.93 | CA1 (0.62) | BBOX1CA1FABP3 | |
| Tetrylammonium SCHEMBL8533424 | 0.92 | BBOX1 (0.56) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Myristic Acid SCHEMBL5153714 | 0.91 | FABP3 (0.62) | BBOX1CA1FABP3 | |
| Octanoic Acid SCHEMBL5574283 | 0.91 | FABP3 (0.62) | BBOX1CA1FABP3 | |
| Palmitic Acid SCHEMBL5153293 | 0.91 | FABP3 (0.62) | BBOX1CA1FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115939421-A | Zirconia-stabilized solid oxide battery fuel electrode material and preparation method and application thereof | 中国科学技术大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-112387251-B | MOF material embedded with iron-containing chelating agent, and synthesis method and application thereof | 西藏大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-109286018-B | Preparation method of ultrathin two-dimensional carbon sheet | 中国科学院兰州化学物理研究所 | 2021-12-31 | — | — | CN | disclosed |
| CN-113304177-A | Wall-broken ganoderma lucidum spore powder extract and preparation method and application of disintegrating tablet thereof | 金华寿仙谷药业有限公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-113087115-A | Method for removing heavy metal complex in wastewater | 广东工业大学 | 2021-07-09 | — | — | CN | disclosed |
| CN-112387251-A | MOF material embedded with iron-containing chelating agent, and synthesis method and application thereof | 西藏大学 | 2021-02-23 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-4255553-A | COMPRISING A COMPOUND HAVING AT LEAST TWO EPOXY GROUPS, A POLYESTER OR ACRYLIC RESIN, AND A QUARTERNARY AMMONIUM CARBOXYLATE AS CATALYST | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1981-03-10 | — | — | US | disclosed |