Methylmalonic Acid

Methylmalonic Acid

SCHEMBL5874817

CC(C(=O)O)C(=O)O.CCCN(CCC)CCC

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.41
CA9 Q16790 3/20 0.41
CA2 P00918 2/20 0.41
DRD3 P35462 2/20 0.39
CHRM1 P11229 1/20 0.39
AKR1A1 P14550 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.36
NPBWR1 P48145 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MCHR1 Q99705 1/20 0.36
CA1 P00915 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylmalonic Acid SCHEMBL5874814 1.00 CA12 (0.41) CA12CA9CA2DRD3CHRM1
Methylmalonic Acid SCHEMBL5874387 0.86 KDM5A (0.46) CA12CA9CA2CA1MAPK1
Methylmalonic Acid SCHEMBL5874382 0.86 KDM5A (0.46) CA12CA9CA2CA1MAPK1
Lactic Acid SCHEMBL21145132 0.85 TP53 (0.55) CA12CA9CA2DRD3CHRM1
Bicarbonate SCHEMBL5875232 0.81 CA12 (0.50) CA12CA9CA2DRD3ADRA1A
Bicarbonate SCHEMBL5875239 0.81 CA12 (0.50) CA12CA9CA2DRD3ADRA1A
Methylmalonic Acid SCHEMBL7714182 0.81 HDAC1 (0.48) CA2DRD3CHRM1AKR1A1CHRM3
Cadaverine Tartrate SCHEMBL5874575 0.80 TSHR (0.50) CA12CA9CA2DRD3CHRM1
Dichloroacetic Acid SCHEMBL5874927 0.80 LMNA (0.50) CA12CA9CA2DRD3CHRM1
Cadaverine Tartrate SCHEMBL5874580 0.80 TSHR (0.50) CA12CA9CA2DRD3CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed