Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | PPARG | P37231 | 7/20 | 0.59 |
| ▸ | PPARD | Q03181 | 7/20 | 0.59 |
| ▸ | PPARA | Q07869 | 7/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TLR2 | O60603 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | FABP4 | P15090 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL5874828 | 1.00 | AKR1B1 (0.62) | AKR1B1LMNAGPR84PPARGPPARD | |
| Azelaic Acid SCHEMBL4399605 | 0.97 | GPR84 (0.64) | AKR1B1LMNAGPR84PPARGPPARD | |
| Sebacic Acid SCHEMBL5875424 | 0.97 | GPR84 (0.64) | AKR1B1LMNAGPR84PPARGPPARD | |
| Sebacic Acid SCHEMBL5875420 | 0.97 | GPR84 (0.64) | AKR1B1LMNAGPR84PPARGPPARD | |
| Glutarate SCHEMBL5875264 | 0.94 | SLC22A6 (0.61) | AKR1B1LMNAGPR84PPARGPPARD | |
| Glutarate SCHEMBL5875257 | 0.94 | SLC22A6 (0.61) | AKR1B1LMNAGPR84PPARGPPARD | |
| Hexanoate SCHEMBL5875370 | 0.93 | AKR1B1 (0.76) | AKR1B1LMNAGPR84PPARGPPARD | |
| Octanoic Acid SCHEMBL5183856 | 0.91 | GPR84 (0.77) | AKR1B1LMNAGPR84PPARGPPARD | |
| Palmitic Acid SCHEMBL10533983 | 0.91 | GPR84 (0.77) | AKR1B1LMNAGPR84PPARGPPARD | |
| Stearic Acid SCHEMBL557515 | 0.91 | GPR84 (0.77) | AKR1B1LMNAGPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-4376713-A | MONO-DIORTRIALKYLAMMONIUM ADIPATE | SPRAGUE ELECTRIC COMPANY (US) | 1983-03-15 | — | — | US | disclosed |