⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28187799 | 0.86 | GSR (0.35) | — | |
| SCHEMBL28087634 | 0.84 | GSR (0.39) | — | |
| SCHEMBL1396066 | 0.79 | ALDH1A1 (0.38) | — | |
| SCHEMBL4260594 | 0.79 | — | — | |
| SCHEMBL174379 | 0.79 | — | — | |
| SCHEMBL8814797 | 0.78 | — | — | |
| SCHEMBL7147126 | 0.78 | — | — | |
| SCHEMBL61052 | 0.78 | — | — | |
| SCHEMBL8998302 | 0.78 | TSHR (0.38) | — | |
| SCHEMBL29163896 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111481218-A | System and method for home transdermal GFR monitoring | 麦迪贝肯有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-111436947-A | Two-piece sensor assembly and method of use | 麦迪贝肯有限公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-111410622-A | Synthesis method of L-cystathionine hydrochloride | 康化（上海）新药研发有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-110740994-A | Peptide Nucleic Acid (PNA) monomers with orthogonally protected ester moieties | 特鲁科德基因修复公司 | 2020-01-31 | — | — | CN | disclosed |
| US-7018792-B2 | trifunctional biosensors comprising alkyl chains for attachment to substrates, fluorescent dyes for generation of fluorescent signals and recognition moiety capable of binding with neuraminidase, used for the detection of influenza virus | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-03-28 | — | — | US | disclosed |
| US-20060003318-A1 | INFLUENZA SENSOR | LOS ALAMOS NATIONAL SECURITY, LLC | 2006-01-05 | — | — | US | disclosed |
| US-6893814-B2 | Influenza sensor | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-17 | — | — | US | disclosed |
| US-20040058315-A1 | Influenza sensor | LOS ALAMOS NATIONAL SECURITY, LLC | 2004-03-25 | — | — | US | disclosed |
| US-6627396-B1 | For detection of tetrameric multivalent neuraminidase within a sample, indicating presence of a virus; recognition molecules bound to trifunctional linker which includes a fluorescence label; binding causes detectable signal | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-09-30 | — | — | US | disclosed |