SCHEMBL7147126

SCHEMBL7147126

NOC(=O)[C@H](N)CCS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7147125 1.00
SCHEMBL936368 0.88 ENPEP (0.41)
SCHEMBL1486704 0.83 ENPEP (0.41)
SCHEMBL5988945 0.82 PTGS1 (0.44)
SCHEMBL17361173 0.81
SCHEMBL4439365 0.80 ANPEP (0.36)
SCHEMBL876613 0.80
SCHEMBL169397 0.80
SCHEMBL111101 0.79
SCHEMBL111100 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3596474-B1 METHOD FOR THE CHROMATOGRAPHIC QUANTITATIVE DETERMINATION OF THE AMINO ACIDS VALINE, METHIONINE, ALLO-ISOLEUCINE, ISOLEUCINE, LEUCINE, TYROSINE AND PHENYLALANINE IN BLOOD PLASMA MEMBRAPURE GMBH (DE) 2021-02-17 EP claimed
EP-3596474-A1 METHOD FOR THE CHROMATOGRAPHIC QUANTITATIVE DETERMINATION OF THE AMINO ACIDS VALINE, METHIONINE, ALLO-ISOLEUCINE, ISOLEUCINE, LEUCINE, TYROSINE AND PHENYLALANINE IN BLOOD PLASMA Membrapure GmbH (DE) 2020-01-22 EP disclosed
WO-2018166546-A1 METHOD FOR THE CHROMATOGRAPHIC QUANTITATIVE DETERMINATION OF THE AMINO ACIDS VALINE, METHIONINE, ALLO-ISOLEUCINE, ISOLEUCINE, LEUCINE, TYROSINE AND PHENYLALANINE IN BLOOD PLASMA MEMBRAPURE GMBH (DE) 2018-09-20 WO disclosed
EP-0726322-B2 Homocysteine assay AXIS SHIELD ASA (NO) 2011-12-07 EP disclosed
EP-0726322-B1 Homocysteine assay AXIS SHIELD ASA (NO) 2003-04-16 EP disclosed
WO-2001056609-A1 PHARMACEUTICAL COMPOSITION FOR TREATING HYPERHOMOCYSTEINAEMIA CAUSED BY MEDICAMENTS WESTPHAL SABINE (DE) 2001-08-09 WO disclosed
US-6063581-A DETECTING COMPOUND IN SAMPLE USING ANTIBODIES; INCUBATION OF SAMPLE WITH HYDROLASE ENZYME AND ADENOSINE, DETECTING THE PRESENCE OF PRODUCTS WITH HAPTENS AND MONOCLONAL ANTIBODIES AXIS-SHIELD ASA (NO) 2000-05-16 US disclosed
US-5958717-A Immunoassay for homocysteine AXIS BIOCHEMICALS ASA (NO) 1999-09-28 US disclosed
US-5827645-A Homocysteine assay AXIS BIOCHEMICALS AS (NO) 1998-10-27 US disclosed
US-5631127-A Enzymatic assay for homocysteine and a kit therefor AXIS BIOCHEMICALS AS (NO) 1997-05-20 US disclosed
EP-0623174-B1 HOMOCYSTEINE ASSAY AXIS BIOCHEMICALS AS (NO) 1996-09-04 EP disclosed
EP-0726322-A1 Homocysteine assay AXIS BIOCHEMICALS AS (NO) 1996-08-14 EP disclosed
EP-0623174-A1 HOMOCYSTEINE ASSAY. COCKBAIN JULIAN R M (GB) 1994-11-09 EP disclosed
WO-1993015220-A1 HOMOCYSTEINE ASSAY AXIS BIOCHEMICALS AS (NO) 1993-08-05 WO disclosed