Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.55 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6267698 | 0.98 | QPCT (0.54) | QPCTQPCTLIDO1TDO2IMPDH2 | |
| SCHEMBL3260750 | 0.78 | QPCT (0.67) | QPCTQPCTLIDO1TDO2CYP17A1 | |
| SCHEMBL12698760 | 0.76 | QPCT (0.68) | QPCTQPCTLIDO1TDO2CYP17A1 | |
| SCHEMBL3231053 | 0.74 | QPCT (0.66) | QPCTQPCTLIDO1TDO2CYP17A1 | |
| SCHEMBL3215934 | 0.74 | QPCT (0.66) | QPCTQPCTLIDO1TDO2CYP17A1 | |
| SCHEMBL12698831 | 0.72 | QPCT (0.59) | QPCTQPCTLIDO1TDO2CYP17A1 | |
| SCHEMBL12698953 | 0.72 | QPCT (0.55) | QPCTQPCTLIDO1TDO2CYP17A1 | |
| SCHEMBL13574557 | 0.71 | FYN (0.38) | TDO2IMPDH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3228833 | 0.71 | QPCT (0.54) | QPCTQPCTLIDO1TDO2CYP17A1 | |
| SCHEMBL3229481 | 0.71 | QPCT (0.54) | QPCTQPCTLIDO1TDO2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006508970-A | — | — | 2006-03-16 | — | — | JP | claimed |
| EP-1565463-A1 | IMIDAZO[1,5A]PYRIDINE DERIVATIVES AND METHODS FOR TREATING ALDOSTERONE MEDIATED DISEASES | Novartis AG (CH) | 2005-08-24 | — | — | EP | claimed |
| WO-2004046145-A1 | IMIDAZO[1, 5A]PYRIDINE DERIVATIVES AND METHODS FOR TREATING ALDOSTERONE MEDIATED DISEASES | NOVARTIS AG (CH) | 2004-06-03 | — | — | WO | claimed |