Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | CHAT | P28329 | 3/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776413 | 0.85 | BACE1 (0.57) | BACE1CHAT | |
| SCHEMBL7776410 | 0.85 | BACE1 (0.57) | BACE1CHAT | |
| SCHEMBL1547489 | 0.84 | RELA (0.46) | BACE1CHATTRPA1NFE2L2PTGS1 | |
| SCHEMBL1547492 | 0.84 | RELA (0.46) | BACE1CHATTRPA1NFE2L2PTGS1 | |
| SCHEMBL1782982 | 0.84 | CHAT (0.68) | CHATPTGS1PTGS2 | |
| SCHEMBL6051064 | 0.84 | CHAT (0.68) | CHATPTGS1PTGS2 | |
| SCHEMBL2774767 | 0.84 | CHAT (0.68) | CHATPTGS1PTGS2 | |
| SCHEMBL29794070 | 0.84 | CHAT (0.68) | CHATPTGS1PTGS2 | |
| Benzene SCHEMBL28841289 | 0.84 | CHAT (0.68) | CHATPTGS1PTGS2 | |
| SCHEMBL39008 | 0.84 | NFE2L2 (0.60) | CHATTRPA1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022867-B2 | Silicon compound and method for making the same | CANON KABUSHIKI KAISHA (JP) | 2006-04-04 | — | — | US | disclosed |
| US-6706839-B1 | COVALENTLY BONDING SEPARATING AGENT TO REACTANT; ISOMERIZATION | UNIVERSITY OF PITTSBURGH | 2004-03-16 | — | — | US | disclosed |
| US-20030216591-A1 | Silicon compound and method for making the same | UENO KAZUNORI (JP) | 2003-11-20 | — | — | US | disclosed |
| EP-1165222-A4 | CHEMICAL PARTITIONING AGENTS AND METHODS OF USING SAME | UNIV PITTSBURGH (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6534198-B1 | Polysilane silicon compound having excellent charge transport characteristics and durability | CANON KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0879841-B1 | Silicon compound, method for making the same, and electroluminescent device using the same | CANON KK (JP) | 2002-10-30 | — | — | EP | disclosed |
| EP-1165222-A1 | CHEMICAL PARTITIONING AGENTS AND METHODS OF USING SAME | UNIVERSITY OF PITTSBURGH (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000047031-A2 | CHEMICAL PARTITIONING AGENTS AND METHODS OF USING SAME | UNIVERSITY OF PITTSBURGH (US) | 2000-08-17 | — | — | WO | disclosed |
| EP-0879841-A2 | Silicon compound, method for making the same, and electroluminescent device using the same | CANON KABUSHIKI KAISHA (JP) | 1998-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216591-A1 | Silicon compound and method for making the same | AR, NR5A1, SSTR1 | BACE1 701/4885CHAT 2068/4885TRPA1 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.