Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878217 | 0.93 | POLB (0.46) | AVPR1AAVPR1B | |
| SCHEMBL5877712 | 0.93 | AVPR1B (0.51) | AVPR1B | |
| SCHEMBL5877695 | 0.92 | AVPR1B (0.46) | AVPR1B | |
| SCHEMBL5877978 | 0.91 | AVPR1B (0.49) | AVPR1B | |
| SCHEMBL5878159 | 0.90 | AVPR1A (0.49) | AVPR1A | |
| SCHEMBL5877858 | 0.89 | AVPR1A (0.49) | AVPR1A | |
| SCHEMBL5877069 | 0.89 | F11 (0.49) | AVPR1B | |
| SCHEMBL5877561 | 0.89 | CYP2D6 (0.46) | AVPR1B | |
| SCHEMBL5876981 | 0.88 | F11 (0.52) | AVPR1B | |
| SCHEMBL5878215 | 0.88 | EGFR (0.48) | AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060706-B1 | Quinazolinones | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-06-13 | — | — | US | disclosed |
| EP-1216233-A1 | QUINAZOLINONES | MERCK PATENT GmbH (DE) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001023364-A1 | QUINAZOLINONES | MERCK PATENT GMBH (DE) | 2001-04-05 | — | — | WO | disclosed |