SCHEMBL5878337

SCHEMBL5878337

NC(=O)c1ccccc1-c1ccc(-c2ccccc2C(N)=O)cc1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.87
CHEK1 O14757 1/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
MAPT P10636 1/20 0.54
HPGD P15428 1/20 0.54
TSHR P16473 1/20 0.54
HSD17B10 Q99714 1/20 0.54
KEAP1 Q14145 1/20 0.52
NFE2L2 Q16236 1/20 0.52
CSNK1A1 P48729 1/20 0.50
TYRO3 Q06418 1/20 0.50
DYRK1B Q9Y463 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
METAP2 P50579 1/20 0.50
ALOX5AP P20292 1/20 0.49
FEN1 P39748 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30582476 0.98 BCAT2 (0.83) BCAT2CHEK1KDM4EALDH1A1MAPT
SCHEMBL31140008 0.94 BCAT2 (0.92) BCAT2CHEK1KDM4EALDH1A1MAPT
SCHEMBL16149659 0.93 BCAT2 (0.91) BCAT2CHEK1KDM4EALDH1A1MAPT
SCHEMBL29427545 0.93 BCAT2 (1.00) BCAT2CHEK1KDM4EALDH1A1MAPT
SCHEMBL132986 0.93 BCAT2 (1.00) BCAT2CHEK1KDM4EALDH1A1MAPT
SCHEMBL8668460 0.92 BCAT2 (0.74) BCAT2CHEK1KDM4EALDH1A1MAPT
SCHEMBL4085068 0.92 BCAT2 (0.74) BCAT2CHEK1KDM4EALDH1A1MAPT
SCHEMBL1982663 0.92 BCAT2 (0.74) BCAT2CHEK1KDM4EALDH1A1MAPT
SCHEMBL656983 0.91 BCAT2 (0.88) BCAT2CHEK1KDM4ETSHRNPC1
Hydrochloric Acid SCHEMBL1785690 0.91 BCAT2 (0.96) BCAT2CHEK1KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7034102-B2 Polylactic acid resin composition and molded article thereof, and process of producing the molded article ASAHI DENKA CO., LTD. (JP) 2006-04-25 US disclosed
EP-1477526-A1 Polyactic acid resin composition and molded article thereof, and process of producing the molded article Asahi Denka Co., Ltd. (JP) 2004-11-17 EP disclosed
US-20040214983-A1 Polylactic acid resin composition and molded article thereof, and process of producing the molded article ASAHI DENKA CO., LTD (JP) 2004-10-28 US disclosed
EP-0379055-B1 Mesogenic advanced epoxy compounds DOW CHEMICAL CO (US) 1999-11-10 EP disclosed
US-5266661-A Epoxy resins THE DOW CHEMICAL COMPANY (US) 1993-11-30 US disclosed
EP-0379055-A2 Mesogenic advanced epoxy compounds THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed
US-4568733-A AIRCRAFT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1986-02-04 US disclosed