Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 19/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 16/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.62 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879340 | 0.87 | OPRD1 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6394863 | 0.80 | OPRD1 (0.88) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879400 | 0.78 | OPRD1 (0.69) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6865749 | 0.77 | OPRD1 (0.83) | OPRD1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL9785691 | 0.77 | CHRM3 (0.78) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6870724 | 0.76 | OPRD1 (0.77) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879329 | 0.76 | OPRD1 (0.81) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6326841 | 0.75 | OPRD1 (0.84) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6325559 | 0.75 | OPRD1 (0.74) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6395178 | 0.74 | OPRD1 (0.78) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064137-B2 | Analgesics; anxiolytic agents; gastrointestinal disorders | ASTRAZENECA AB (SE) | 2006-06-20 | — | — | US | disclosed |