Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Sarcosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sarcosine SCHEMBL28981079 | 0.97 | CYP2C19 (0.37) | CYP2C19CTHGRIN2DGRIN3BGRIN1 | |
| Sarcosine SCHEMBL4962879 | 0.87 | CTH (0.39) | CTHGRIN2DGRIN3BGRIN1GRIN2A | |
| Sarcosine SCHEMBL4171569 | 0.87 | CYP2C19 (0.31) | CYP2C19CTH | |
| Sarcosine SCHEMBL30313616 | 0.87 | CTH (0.42) | CTHGRIN2DGRIN3BGRIN1GRIN2A | |
| Sarcosine SCHEMBL177631 | 0.87 | — | — | |
| Sarcosine SCHEMBL16162573 | 0.87 | — | — | |
| Sarcosine SCHEMBL28606783 | 0.87 | CTH (0.42) | CTHGRIN2DGRIN3BGRIN1GRIN2A | |
| Sarcosine SCHEMBL3507420 | 0.85 | APEX1 (0.32) | CYP2C19APEX1ALDH1A1LMNAMAPT | |
| Sarcosine SCHEMBL31427574 | 0.84 | — | — | |
| Sarcosine SCHEMBL149 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041815-B2 | Sporamin promoter and uses thereof | SINON CORPORATION (TW) | 2006-05-09 | — | — | US | disclosed |
| US-20030167518-A1 | Sporamin promoter and uses thereof | PLANTON GMBH (DE) | 2003-09-04 | — | — | US | disclosed |