Sarcosine

Sarcosine

SCHEMBL4171569

CNCC(=O)O.N=C(N)N.N=C=S

nearest known ligand 0.31

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Known targets — ChEMBL curated mechanism

KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2

The experimentally established mechanism targets of Sarcosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.31
CTH P32929 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sarcosine SCHEMBL7892203 0.91
Sarcosine SCHEMBL28981079 0.89 CYP2C19 (0.37) CYP2C19CTH
Sarcosine SCHEMBL5879392 0.87 CYP2C19 (0.36) CYP2C19CTH
Sarcosine SCHEMBL3507420 0.82 APEX1 (0.32) CYP2C19
Sarcosine SCHEMBL29233122 0.80
Sarcosine SCHEMBL4962879 0.79 CTH (0.39) CTH
Sarcosine SCHEMBL149 0.76
Sarcosine SCHEMBL31427574 0.76
Sarcosine SCHEMBL156329 0.76 LDHA (0.44) CTH
Sarcosine SCHEMBL28259932 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090092979-A1 METHODS FOR ISOLATING LONG FRAGMENT RNA FROM FIXED SAMPLES RESPONSE GENETICS, INC. (US) 2009-04-09 US disclosed