Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771547 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL11046668 | 0.79 | GABRA1 (0.46) | KDM4EALDH1A1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL11061861 | 0.79 | GABRA1 (0.42) | KDM4EALDH1A1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL7857061 | 0.78 | MAPK1 (0.51) | KDM4EALDH1A1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL24440339 | 0.76 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL44672 | 0.76 | GABRA1 (0.48) | KDM4EALDH1A1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL9715056 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL14622099 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL3689460 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL5461755 | 0.74 | MRGPRX4 (0.49) | KDM4EALDH1A1SMN1; SMN2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141684-B2 | Diepoxide derivatives of diallyl phenolics | PEWS R GARTH | 2006-11-28 | — | — | US | disclosed |
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | PEWS R G (US) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | EBP, EED, ESR2 | KDM4E 293/4885ALDH1A1 194/4885SMN1; SMN2 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.