SCHEMBL3689460

SCHEMBL3689460

C=CCc1cccc(C(=O)OC)c1C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 4/20 0.45
LMNA P02545 2/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
TSHR P16473 1/20 0.42
HSD17B10 Q99714 3/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
CFTR P13569 1/20 0.41
MAPT P10636 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13881143 0.91 KDM4E (0.45) KDM4EKMT2AMEN1HTTSMN1; SMN2
SCHEMBL11473929 0.87 KDM4E (0.45) KDM4EKMT2AMEN1HTTSMN1; SMN2
SCHEMBL24440339 0.86 KDM4E (0.48) KDM4EKMT2AMEN1HTTSMN1; SMN2
SCHEMBL24074659 0.85 ALDH1A1 (0.57) KDM4EKMT2AMEN1HTTSMN1; SMN2
SCHEMBL6274334 0.84 MEN1 (0.55) KDM4EKMT2AMEN1HTTSMN1; SMN2
SCHEMBL29266193 0.83 ALDH1A1 (0.47) KDM4EKMT2AMEN1HTTSMN1; SMN2
SCHEMBL22445329 0.83 BDKRB1 (0.44) KDM4EKMT2AMEN1HTTSMN1; SMN2
SCHEMBL1802101 0.83 ALDH1A1 (0.44) KDM4EKMT2AMEN1HTTSMN1; SMN2
SCHEMBL11355913 0.83 GABRA1 (0.42) KDM4EKMT2AMEN1HTTSMN1; SMN2
Hydroxyamine SCHEMBL31418669 0.82 MEN1 (0.53) KDM4EKMT2AMEN1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
WO-2012158415-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-11-22 WO disclosed
US-7803298-B2 Molding material, molded part, and method for manufacturing them SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2010-09-28 US disclosed
US-7759356-B2 Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods JANSSEN PHARMACEUTICA, N.V. (BE) 2010-07-20 US disclosed
US-7754730-B2 Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2010-07-13 US disclosed
US-20090085260-A1 BIODEGRADABLE MATERIAL AND PROCESS FOR PRODUCING THE SAME JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 2009-04-02 US disclosed
US-20090054429-A1 ARYLINDENOPYRIDINES AND ARYLINDENOPYRIMIDINES AND RELATED THERAPEUTIC AND PROPHYLACTIC METHODS JANSSEN PHARMACEUTICA NV (BE) 2009-02-26 US disclosed
US-20090030160-A1 Polylactic Acid Complex and Production Method Thereof SUMITOMO ELECTRIC FINE POLYMER INC. (JP) 2009-01-29 US disclosed
US-7468373-B2 Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2008-12-23 US disclosed
US-20080213209-A1 Process for Producing Cross-Linked Material of Polylactic Acid and Cross-Linked Material of Polylactic Acid SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2008-09-04 US disclosed
US-7345052-B2 Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2008-03-18 US disclosed
US-7345052-B2 Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2008-03-18 US disclosed
US-20080036119-A1 Molding material, molded part, and method for manufacturing them SUMITOMO ELECTRIC FINE POLYMER, INC. 2008-02-14 US disclosed
US-20070155760-A1 ARYLINDENOPYRIDINES AND ARYLINDENOPYRIMIDINES AND RELATED THERAPEUTIC AND PROPHYLACTIC METHODS JANSSEN PHARMACEUTICA NV (BE) 2007-07-05 US disclosed
US-20070155760-A1 ARYLINDENOPYRIDINES AND ARYLINDENOPYRIMIDINES AND RELATED THERAPEUTIC AND PROPHYLACTIC METHODS JANSSEN PHARMACEUTICA NV (BE) 2007-07-05 US disclosed
US-20060160984-A1 Biodegradable material and process for producing the same JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 2006-07-20 US disclosed
US-20050242466-A1 Process for producing transparent material made of polylactic acid and transparent material made of polylactic acid SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2005-11-03 US disclosed
WO-2005042500-A1 ARYLINDENOPYRIDINES AND ARYLINDENOPYRIDINES AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONIST ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2005-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070155760-A1 ARYLINDENOPYRIDINES AND ARYLINDENOPYRIMIDINES AND RELATED THERAPEUTIC AND PROPHYLACTIC METHODS ADORA2A, ADORA1, ADORA3 KDM4E 2705/4885KMT2A 2094/4885MEN1 3809/4885
US-20090085260-A1 BIODEGRADABLE MATERIAL AND PROCESS FOR PRODUCING THE SAME TST, PCMT1, XRCC6 KDM4E 2178/4885KMT2A 1444/4885MEN1 214/4885
US-20090054429-A1 ARYLINDENOPYRIDINES AND ARYLINDENOPYRIMIDINES AND RELATED THERAPEUTIC AND PROPHYLACTIC METHODS ADORA2A, ADORA1, ADORA3 KDM4E 2705/4885KMT2A 2094/4885MEN1 3809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.