Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.53 |
| ▸ | ITGAV | P06756 | 11/20 | 0.53 |
| ▸ | SLC40A1 | Q9NP59 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879901 | 0.79 | ITGB3 (0.73) | ITGB3ITGAV | |
| SCHEMBL5879555 | 0.76 | ITGB3 (0.64) | ITGB3ITGAV | |
| SCHEMBL5879562 | 0.75 | ITGB3 (0.56) | ITGB3ITGAVSLC40A1SMN1; SMN2 | |
| SCHEMBL5879791 | 0.75 | ITGB3 (0.74) | ITGB3ITGAV | |
| SCHEMBL5879538 | 0.73 | ITGB3 (0.73) | ITGB3ITGAV | |
| SCHEMBL5879582 | 0.72 | ITGB3 (0.74) | ITGB3ITGAV | |
| SCHEMBL5879540 | 0.71 | ITGB3 (0.63) | ITGB3ITGAV | |
| Hydrochloric Acid SCHEMBL5879699 | 0.69 | ITGB3 (0.98) | ITGB3ITGAV | |
| SCHEMBL5879517 | 0.67 | ITGB3 (0.72) | ITGB3ITGAV | |
| SCHEMBL6700952 | 0.67 | TSHR (0.52) | ITGB3ITGAVSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |