Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.56 |
| ▸ | ITGAV | P06756 | 6/20 | 0.56 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879558 | 0.86 | ITGB3 (0.74) | ITGB3ITGAV | |
| SCHEMBL5879510 | 0.78 | GRIN2B (0.41) | ITGB3ITGAV | |
| SCHEMBL5025645 | 0.78 | ITGB3 (0.54) | ITGB3ITGAVSLC40A1 | |
| SCHEMBL5025680 | 0.78 | ITGB3 (0.47) | ITGB3ITGAVSMN1; SMN2SLC40A1 | |
| SCHEMBL5879571 | 0.75 | ITGB3 (0.53) | ITGB3ITGAVSMN1; SMN2SLC40A1 | |
| SCHEMBL5879621 | 0.70 | ITGB3 (0.51) | ITGB3ITGAVMAPK1 | |
| SCHEMBL5879569 | 0.70 | ITGB3 (0.51) | ITGB3ITGAVMAPK1MAPT | |
| SCHEMBL5879664 | 0.70 | ITGB3 (0.52) | ITGB3ITGAVMEN1ALDH1A1KMT2A | |
| SCHEMBL5879751 | 0.68 | ITGB3 (0.49) | ITGB3ITGAVMAPTMEN1ALDH1A1 | |
| SCHEMBL5879692 | 0.65 | NOS2 (0.48) | ITGB3ITGAVSMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |