Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879529 | 0.85 | CA12 (0.49) | HTR6ALDH1A1L3MBTL1DRD2NPSR1 | |
| SCHEMBL4488667 | 0.70 | HTR6 (0.57) | HTR6ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL6548713 | 0.69 | HTR6 (0.71) | HTR6ALDH1A1L3MBTL1DRD2HTR2C | |
| SCHEMBL1136509 | 0.68 | HTR6 (1.00) | HTR6ALDH1A1L3MBTL1DRD2HTR2C | |
| SCHEMBL4480306 | 0.67 | HTR6 (0.51) | HTR6ALDH1A1L3MBTL1DRD2HTR2C | |
| SCHEMBL4480373 | 0.67 | HTR6 (0.56) | HTR6ALDH1A1L3MBTL1DRD2HTR2C | |
| SCHEMBL27563317 | 0.66 | HTR6 (0.58) | HTR6ALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL2197288 | 0.65 | HTR6 (0.80) | HTR6ALDH1A1L3MBTL1DRD2HTR2C | |
| SCHEMBL3950671 | 0.65 | HTR6 (0.63) | HTR6ALDH1A1L3MBTL1DRD2HTR2C | |
| SCHEMBL15503471 | 0.65 | HTR6 (0.80) | HTR6ALDH1A1L3MBTL1DRD2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006517966-A | — | — | 2006-08-03 | — | — | JP | claimed |
| EP-1592690-A1 | HETEROCYCLYL-3-SULFONYLAZAINDOLE OR -AZAINDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | Wyeth (US) | 2005-11-09 | — | — | EP | claimed |
| WO-2004074286-A1 | HETEROCYCLYL-3-SULFONYLAZAINDOLE OR -AZAINDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2004-09-02 | — | — | WO | claimed |