Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524126 | 0.83 | ALDH1A1 (0.67) | POLBCA12CA9ALDH1A1KMT2A | |
| SCHEMBL27703398 | 0.82 | ALDH1A1 (0.72) | POLBALDH1A1AGTR1KMT2AMAPT | |
| SCHEMBL1444562 | 0.77 | POLB (0.54) | POLBALDH1A1AGTR1KMT2AMEN1 | |
| SCHEMBL1444561 | 0.77 | POLB (0.54) | POLBALDH1A1AGTR1KMT2AMEN1 | |
| SCHEMBL5879566 | 0.77 | ITGB3 (0.54) | POLBCA12CA9 | |
| SCHEMBL30788174 | 0.77 | POLB (0.60) | POLBALDH1A1AGTR1KMT2AMAPT | |
| SCHEMBL522649 | 0.77 | CA12 (1.00) | CA12CA9ALDH1A1KMT2AMAPT | |
| SCHEMBL29744481 | 0.77 | CA12 (1.00) | CA12CA9ALDH1A1KMT2AMAPT | |
| SCHEMBL20864615 | 0.76 | POLB (1.00) | POLBALDH1A1MAPT | |
| SCHEMBL3012558 | 0.76 | CES1 (0.65) | POLBCA12CA9ALDH1A1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |