Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.49 |
| ▸ | ITGAV | P06756 | 16/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879576 | 0.91 | ITGB3 (0.54) | ITGB3ITGAV | |
| SCHEMBL5879512 | 0.89 | ITGB3 (0.44) | ITGB3ITGAV | |
| SCHEMBL5879566 | 0.87 | ITGB3 (0.54) | ITGB3ITGAVCA12CA9 | |
| SCHEMBL5880062 | 0.83 | CYP1A2 (0.42) | ITGB3ITGAV | |
| SCHEMBL5879532 | 0.80 | KDR (0.37) | ITGB3ITGAV | |
| SCHEMBL5879521 | 0.80 | POLB (0.46) | ITGB3ITGAV | |
| SCHEMBL5879502 | 0.79 | ITGB3 (0.41) | ITGB3ITGAV | |
| SCHEMBL5026289 | 0.75 | ITGB3 (0.42) | ITGB3ITGAV | |
| SCHEMBL5023976 | 0.75 | ITGB3 (0.42) | ITGB3ITGAV | |
| SCHEMBL5025707 | 0.75 | ITGB3 (0.42) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |