Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.35 |
| ▸ | ITGAV | P06756 | 5/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879694 | 0.87 | EGFR (0.41) | KDRALDH1A1HPGDITGB3ITGAV | |
| SCHEMBL5879591 | 0.80 | ITGB3 (0.49) | ITGB3ITGAV | |
| SCHEMBL5879512 | 0.78 | ITGB3 (0.44) | HDAC3HDAC1HDAC8HDAC6ITGB3 | |
| SCHEMBL5880062 | 0.77 | CYP1A2 (0.42) | HDAC3HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL5879657 | 0.76 | EGFR (0.37) | KDRALDH1A1TSHRKMT2A | |
| SCHEMBL5879576 | 0.76 | ITGB3 (0.54) | ITGB3ITGAV | |
| SCHEMBL5879502 | 0.71 | ITGB3 (0.41) | HDAC3HDAC1HDAC8HDAC6ITGB3 | |
| SCHEMBL7402874 | 0.71 | BRD4 (0.39) | BRD4HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL5879521 | 0.69 | POLB (0.46) | HDAC3HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL7074976 | 0.68 | MTNR1B (0.35) | HDAC3HDAC1HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |